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dc.contributor.authorDincel, DEMET
dc.contributor.authorHatipoglu, Seda Damla
dc.contributor.authorGOREN, AHMET CEYHAN
dc.contributor.authorTopcu, Gulacti
dc.date.accessioned2019-10-05T14:37:49Z
dc.date.available2019-10-05T14:37:49Z
dc.date.issued2013-01-01
dc.identifier
dc.identifier.citationDincel D., Hatipoglu S. D. , GOREN A. C. , Topcu G., -Anticholinesterase furocoumarins from Heracleum platytaenium, a species endemic species to Ida Mountains-, TURKISH JOURNAL OF CHEMISTRY, cilt.37, ss.675-683, 2013
dc.identifier.urihttps://hdl.handle.net/20.500.12645/4327
dc.identifier.urihttps://journals.tubitak.gov.tr/chem/index.htm
dc.description.abstractThe petroleum ether extract of Heracleum platytaenium afforded 8 furocoumarins (psoralen, bergapten, xanthotoxin, pimpinellin, isopimpinellin, sphondin, byakangelicin, and heraclenol) and the methanol extract of H. platytaenium gave only 1 glycosylated dihydrofurocoumarin, apterin. In addition, stigmasterol was also obtained from petroleum ether extract. Structure identification of the isolated compounds has been achieved by using spectroscopic methods, namely 1D and 2D NMR experiments and mass spectral analyses. The antioxidant activity of the extracts and pure compounds was investigated by 2 methods, including DPPH free radical scavenging activity and lipid peroxidation inhibitory activity by beta-carotene-linoleic acid assays. The anticholinesterase activity of petroleum ether and methanol extracts of the plant and the isolated furocoumarins was investigated against acetylcholinesterase and butyrylcholinesterase enzymes by the Ellman method in vitro.
dc.language.isoen
dc.subjectHeracleum platytaenium
dc.titleAnticholinesterase furocoumarins from Heracleum platytaenium, a species endemic species to Ida Mountains
dc.typeArticle
local.avesis.response4197
local.article.journalnameINTERNATIONAL JOURNAL OF CLINICAL PHARMACY
dc.identifier.wosWOS:000321817800014
dc.contributor.institutionauthorGÖREN, AHMET CEYHAN


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