Welcome to the Open Access System!


This site is Bezmialem Vakif University Academic Open Access System. The system was established in June 2019 in order to store the academic outcomes of Bezmialem Vakif University in digital standards and to provide them with open access. OpenAccess includes academic outputs such as articles, presentations, dissertations, books, book chapters and reports produced by Bezmialem Vakif University.


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Recent Submissions

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Role of cell-free DNA and extracellular vesicles for diagnosis and surveillance in patients with glioma
(2024-01-01) Karaçam B.; Elbasan E. B.; Khan I.; Akdur K.; Mahfooz S.; Merve C.; Yusuf C.; Hatiboğlu M. A.; KARAÇAM, BÜŞRA; HATİBOĞLU, MUSTAFA AZİZ
Objectives: Liquid biopsy can be used to make the diagnosis, to screen treatment response, and to predict the prognosis. Extracellular vesicles (EVs) and cell-free DNA (cfDNA) sources are used as liquid biopsy biomarkers from body fluids such as serum, cerebrospinal fluid, urine, and mucosa. The purpose of this study was to investigate whether EVs and cfDNA are predictive for diagnosis and prognosis in patients with glioma. Methods: cfDNA and EVs levels were measured from 17 glioma patients at three different time intervals (before surgery, 10–14 days after surgery, and at the time of recurrence) and 7 healthy individuals. We investigated whether their level increased in glioma patients. Also, the correlation between clinical outcome and their levels was analyzed. Results: The mean serum cfDNA level in glioma patients was found to be higher compared to that in healthy controls. The difference between cfDNA level before surgery and that at 3 months follow-up was found to be statistically significant. Also, the mean serum EVs level in the glioma patients was found to be significantly higher compared to that in the control group. Discussion: Our results suggested that cfDNA and EVs could be used as diagnostic biomarkers in patients with glioma. cfDNA could be also a possible biomarker for the surveillance of glioma patients. Further studies are warranted to confirm our findings
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Sleep Hygiene Education in Adolescents: The Role of the Pediatric Nurses
(2024-02-01) Koyuncuoğlu E.; Gözen D.; KOYUNCUOĞLU, ELİF
Pediatric nurses have an essential role in promoting adolescent health. Adolescence is a vital childhood period. This period is the transition from childhood to adulthood, and the mainstay of a healthy life occurs. Adolescents’ needs and risks should be considered to continue their growth and development. Sleep is an essential factor influencing adolescent health, such as nutrition, physical activity, psychosocial environment, and risky behaviors. Sleep is directly related to situations such as physical health, the development of cognitive skills, and risky behaviors for adolescents. If adolescents do not have adequate and quality sleep, they face various problems such as learning difficulties, low academic success, accidents, and injuries. Sleep hygiene programs are beneficial for preventing adolescent’s sleep problems. Sleep hygiene programs contain parameters such as creating a sleep schedule, regulating daily physical activity and eating habits, creating a pre-sleep routine, reducing caffeine consumption, and creating a sleep environment. Pediatric nurses lead sleep hygiene education programs together with adolescents’ parents, teachers, and healthcare professionals. It is recommended to develop games and web-based alternative designs. Games and web-based designs increase the effectiveness of sleep hygiene programs. This article aimed to emphasize the importance of sleep health in adolescents and the roles of pediatric nurses. Sleep hygiene practices are essential to develop healthy sleep patterns in adolescents. The article points out the roles of pediatric nurses, such as educators, guides, and consultants, in promoting the sleep health of adolescents. Keywords: Adolescent, sleep hygiene education, pediatric nursing.
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Ketojenik Diyetin Sporcular Üzerine Etkisi
(Vize Yayıncılık, 2024-02-01) Mendeş B.; MENDEŞ, BEYZA
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