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The correlation between breast cancer and urinary iodine excretion levels

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Date
2018-02-01
Author
Guzel, MEHMET
Kadioglu, HÜSEYİN
Hasbahçeci, Mustafa
Malya, FATMA ÜMİT
Dolay, KEMAL
Ersoy, YELİZ EMİNE
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Type
Article
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Abstract
Objective To compare urinary iodine excretion levels in patients with breast cancer and control subjects. Methods In this prospective pilot study, patients with breast cancer and normal controls were recruited. Age and menopausal status were recorded. Levels of serum thyroid-stimulating hormone, blood urea nitrogen and creatinine and urine iodine concentration (UIC) were measured. UIC levels were divided into three categories: low (<100 µg/l), normal (100-200 µg/l) or high (>200 µg/l). Results A total of 24 patients with breast cancer and 48 controls were included in the study. There were no statistically significant differences between the two groups with regard to thyroid-stimulating hormone, blood urea nitrogen or creatinine levels. When considered overall, there was no statistical difference in UIC between patients and controls. However, comparisons within each category (low, normal or high UIC) showed a significantly higher percentage of patients with breast cancer had a high UIC compared with controls. Conclusions A high UIC was seen in a significantly higher percentage of patients with breast cancer than controls. UIC may have a role as a marker for breast cancer screening. Further studies evaluating UIC and iodine utilization in patients with breast cancer are warranted.
Subject
Malya F. Ü. , Kadioglu H., Hasbahçeci M., Dolay K., Guzel M., Ersoy Y. E. , -The correlation between breast cancer and urinary iodine excretion levels-, JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, cilt.46, ss.687-692, 2018
URI
https://hdl.handle.net/20.500.12645/1404
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BEZMIALEM VAKIF UNIVERSITY

About us |Policies | Library | Contact us | Send Feedback | Sitemap | Admin

Bezmialem Vakıf Üniversitesi, Adnan Menderes Bulvarı Vatan Caddesi 34093 Fatih, İstanbul / TURKEY
Copyright © Bezmialem Vakıf Üniversitesi

Creative Commons Lisansı
Bezmialem Institutional Repository, Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

OpenAccess@BVU

Support by  UNIREPOS