Publication: Serum and tonsil tissue melatonin levels o fpatients with chronic tonsillitis
No Thumbnail Available
Date
2019-03-01
Authors
ŞENTÜRK, EROL
YILDIRIM, YAVUZ SELİM
ÇALIM, ÖMER FARUK
YENİGÜN, ALPER
Ozturan, Orhan
Kepekçi Tekkeli, Şerife Evrim
Kızıltaş, Mustafa Volkan
Journal Title
Journal ISSN
Volume Title
Publisher
Metrics
Abstract
Objectives: This study aims to compare the serum, tonsil surface
epithelial tissue and parenchyma levels of melatonin in children
who underwent tonsillectomy due to recurrent tonsillitis.
Patients and Methods: The study included 33 pediatric
patients (17 males, 16 females; mean age 7.3 years; range, 3 to 10
years) scheduled for tonsillectomy surgery. Five milliliter venous
blood samples and 25 g of two different types of tonsil tissues,
parenchyma and capsule were collected from the patients and
stored. High performance liquid chromatography was used for
the determination of melatonin in plasma and tissue samples.
Results: The tonsil surface tissue levels of melatonin were
lower than the simultaneous plasma levels of melatonin
(p<0.0135). The plasma levels of melatonin were higher than
the simultaneous tonsil parenchyma tissue levels of melatonin
(p<0.016). The tonsil surface tissue levels of melatonin were
lower than the simultaneous tonsil parenchyma tissue levels of
melatonin (p<0.002).
Conclusion: The plasma concentrations of melatonin and
tonsil surface epithelial tissue and parenchyma concentrations
of melatonin in children with chronic tonsillitis were low.
According to this finding, we may recommend serum levels of
melatonin to be checked in patients indicated for tonsillectomy
Description
Keywords
Citation
ŞENTÜRK E., YILDIRIM Y. S. , ÇALIM Ö. F. , YENİGÜN A., Ozturan O., Kepekçi Tekkeli Ş. E. , Kızıltaş M. V. , -Serum and tonsil tissue melatonin levels o fpatients with chronic tonsillitis-, KBB UYGULAMALARI, cilt.7, ss.80-84, 2019