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Serum and tonsil tissue melatonin levels o fpatients with chronic tonsillitis

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dc.contributor.authorŞENTÜRK, EROL
dc.contributor.authorYILDIRIM, YAVUZ SELİM
dc.contributor.authorÇALIM, ÖMER FARUK
dc.contributor.authorYENİGÜN, ALPER
dc.contributor.authorOzturan, Orhan
dc.contributor.authorKepekçi Tekkeli, Şerife Evrim
dc.contributor.authorKızıltaş, Mustafa Volkan
dc.contributor.institutionauthorŞENTÜRK, EROL
dc.contributor.institutionauthorÇALIM, ÖMER FARUK
dc.contributor.institutionauthorYENİGÜN, ALPER
dc.date.accessioned2019-12-21T20:59:37Z
dc.date.available2019-12-21T20:59:37Z
dc.date.issued2019-03-01
dc.description.abstractObjectives: This study aims to compare the serum, tonsil surface epithelial tissue and parenchyma levels of melatonin in children who underwent tonsillectomy due to recurrent tonsillitis. Patients and Methods: The study included 33 pediatric patients (17 males, 16 females; mean age 7.3 years; range, 3 to 10 years) scheduled for tonsillectomy surgery. Five milliliter venous blood samples and 25 g of two different types of tonsil tissues, parenchyma and capsule were collected from the patients and stored. High performance liquid chromatography was used for the determination of melatonin in plasma and tissue samples. Results: The tonsil surface tissue levels of melatonin were lower than the simultaneous plasma levels of melatonin (p<0.0135). The plasma levels of melatonin were higher than the simultaneous tonsil parenchyma tissue levels of melatonin (p<0.016). The tonsil surface tissue levels of melatonin were lower than the simultaneous tonsil parenchyma tissue levels of melatonin (p<0.002). Conclusion: The plasma concentrations of melatonin and tonsil surface epithelial tissue and parenchyma concentrations of melatonin in children with chronic tonsillitis were low. According to this finding, we may recommend serum levels of melatonin to be checked in patients indicated for tonsillectomyen
dc.identifier.citationŞENTÜRK E., YILDIRIM Y. S. , ÇALIM Ö. F. , YENİGÜN A., Ozturan O., Kepekçi Tekkeli Ş. E. , Kızıltaş M. V. , -Serum and tonsil tissue melatonin levels o fpatients with chronic tonsillitis-, KBB UYGULAMALARI, cilt.7, ss.80-84, 2019
dc.identifier.doi10.5606/kbbu.2019.41275
dc.identifier.trdizintrdizin
dc.identifier.urihttps://hdl.handle.net/20.500.12645/10682
dc.identifier.yoksis4980647
dc.language.isoen
dc.titleSerum and tonsil tissue melatonin levels o fpatients with chronic tonsillitis
dc.typeArticle
dspace.entity.typePublication
local.avesis.id8486306e-43d2-46dd-89a8-fc42c5e0e198
local.publication.isinternational0
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relation.isAuthorOfPublicatione9d3c6c5-8d8a-4267-a9ff-0c87df962a63
relation.isAuthorOfPublication.latestForDiscoverye9d3c6c5-8d8a-4267-a9ff-0c87df962a63
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