Publication:
A fatal interstitial lung disease in an anti-melanoma differentiation-associated gene 5 (anti-MDA5) antibody negative patient with juvenile dermatomyositis

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2021-09-01T00:00:00Z
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YEŞİLBAŞ, Osman
Yildiz, Mehmet
Yozgat, Can Yilmaz
Tahaoglu, Irmak
YAZAN, HAKAN
ÇAKIR, Erkan
Adrovic, Amra
Sahin, Sezgin
Barut, Kenan
Kasapcopur, Ozgur
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Research Projects
Sustainable Development Goals
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Background. Juvenile dermatomyositis associated interstitial lung disease, rarely seen in pediatric age groups, has adverse effects on survival. Anti-melanoma differentiation associated gene 5, one of the identified autoantibodies in juvenile dermatomyositis, preferentially affects the lung tissue and may cause rapidly progressive interstitial lung disease. It is a major cause of mortality in juvenile dermatomyositis. In this case report, we present a pediatric patient diagnosed with juvenile dermatomyositis without anti-melanoma differentiation associated gene 5 antibody positivity.
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YEŞİLBAŞ O., Yildiz M., Yozgat C. Y. , Tahaoglu I., YAZAN H., ÇAKIR E., Adrovic A., Sahin S., Barut K., Kasapcopur O., -A fatal interstitial lung disease in an anti-melanoma differentiation-associated gene 5 (anti-MDA5) antibody negative patient with juvenile dermatomyositis-, TURKISH JOURNAL OF PEDIATRICS, cilt.63, sa.5, ss.903-908, 2021