Effects of Intrathecai Verapamil on Cerebral Vasospasm in Experimental Rat Study
Date
2019-07-01Author
Calis, FatihHanimoglu, Hakan
Akkaya, Enes
Evran, Sevket
Cevik, Serdar
Kaynar, Mehmet Yasar
Hatiboglu, Mustafa Aziz
Saglam, Mustafa Yasin
KOÇYİĞİT, ABDÜRRAHİM
Karatas, Ersin
Katar, Salim
SEYİTHANOĞLU, MEHMET HAKAN
Advisor
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BACKGROUND: Verapamil a calcinarn channel blacker, has shown promising results on cerebral vasospasm. However, it has not yet been accepted for treatment or prevention purposes because of the associated side effects, Although the effective results of nimodipine and nicardipine-s intrathecal administration are well known, intrathecal verapamil has not been considered earlier. We used an experimental subarachnoid hemorrhage induced vasospasm model for the evaluation of vasodilator and neuroprotective effects of intrathecal verapamil,
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