Publication: Effects of Intrathecai Verapamil on Cerebral Vasospasm in Experimental Rat Study
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Hatiboglu, Mustafa Aziz
Evran, Sevket
Calis, Fatih
Cevik, Serdar
Hanimoglu, Hakan
SEYİTHANOĞLU, MEHMET HAKAN
Katar, Salim
Karatas, Ersin
KOÇYİĞİT, ABDÜRRAHİM
Saglam, Mustafa Yasin
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Abstract
BACKGROUND: Verapamil a calcinarn channel blacker, has shown promising results on cerebral vasospasm. However, it has not yet been accepted for treatment or prevention purposes because of the associated side effects, Although the effective results of nimodipine and nicardipine-s intrathecal administration are well known, intrathecal verapamil has not been considered earlier. We used an experimental subarachnoid hemorrhage induced vasospasm model for the evaluation of vasodilator and neuroprotective effects of intrathecal verapamil,
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Akkaya E., Evran S., Calis F., Cevik S., Hanimoglu H., SEYİTHANOĞLU M. H. , Katar S., Karatas E., KOÇYİĞİT A., Saglam M. Y. , et al., -Effects of Intrathecai Verapamil on Cerebral Vasospasm in Experimental Rat Study-, WORLD NEUROSURGERY, cilt.127, 2019