Person: KOÇYİĞİT, ABDÜRRAHİM
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Publication Metadata only Timokinon İle İndüklenmiş Gastrik Adenokarsinom Hücrelerinde Sitotoksisite, Genotoksisite ve Apoptoz(2015-11-06T00:00:00Z) GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİMPublication Metadata only Beta-globin gene mutations in children with beta-thalassemia major from Sanliurfa province, Turkey(2011-12-01T00:00:00Z) Aycicek, Ali; Koc, Ahmet; Ozdemir, Zeynep Canan; Bilinc, Hasan; Kocyigit, ABDÜRRAHİM; Dilmec, Fuat; KOÇYİĞİT, ABDÜRRAHİMObjective: The prevalence of (beta-thalassemia in Sanhurfa province, Turkey is reported to be 2.6%-3.7%, whereas nation-wide the frequency of beta-thalassemia is 2%. This study aimed to identify the most frequent beta-thalassemia mutations in Sanhurfa province.Publication Metadata only Toxicity of Sodium Fluoride in Adult Retinal Pigment Epithelial Cells Related to Transepithelial Resistance Mechanism(2020-03-17T00:00:00Z) Erkan, Muhammed Abdulkadir; UMURHAN AKKAN, JÜLİDE CANAN; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; UMURHAN AKKAN, JÜLİDE CANAN; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİMPublication Unknown Oleuropein mide kanserine karşı: Yeni Tedavi Umudu(2018-11-20T00:00:00Z) TÜRKDOĞAN, KÜRŞAD; KOÇYİĞİT, ABDÜRRAHİM; GÜLER, ERAY METİN; ÖZER, ÖMER FARUK; KOÇYİĞİT, ABDÜRRAHİM; GÜLER, ERAY METİN; ÖZER, ÖMER FARUKPublication Unknown Cytotoxic and apoptotic activities of thymol from Thymus vulgaris on the human gastric adenocarcinoma cells(2015-06-10) GÜNEŞ BAYIR, AYŞE; KIZILTAN, HURİYE ŞENAY; GÜLER, ERAY METİN; KARAKAŞ, ERSİN; KOÇYİĞİT, ABDÜRRAHİM; GÜNEŞ BAYIR, AYŞE; KIZILTAN, HURİYE ŞENAY; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİMPublication Unknown Circulating levels of cytokines are increased in restless legs syndrome.(2020-10-21T00:00:00Z) Uslu, FI; Koçyiğit, A; Demir, E; Güler, Eray Metin; USLU, FERDA; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİMBackground: Restless legs syndrome [RLS] is known as a disease of iron and dopaminergic dysregulation but inflammatory processes might also have a role in the pathogenesis. In this study, we compared the circulating levels of hsCRP, IL-1β, IL-6, and TNF-α in patients with primary restless legs syndrome [RLS] and healthy control subjects. Methods: We prospectively included 29 patients with primary RLS and 65 healthy controls [HC], all age-sex matched. The diagnosis of RLS was established using international guidelines. IRLSSG Severity Scale was used to evaluate the severity of RLS. Plasma levels of hsCRP, IL-1β, IL-6, and TNF-α were measured in all participants. Results: The mean age of patients was 37.8 ± 11.3 and 52% of RLS group were women. Serum IL-1β, IL-6, and TNF-α levels of the patient group were statistically significantly higher compared to HC [p < 0.001 for all variables]. Plasma levels of hsCRP did not differ between groups. There were 8 patients with mild RLS [28%], 13 patients with moderate RLS [45%], and 8 patients with severe RLS [28%]. Only IL-6 values were significantly different between the groups. In the severe group, the value of IL-6 was significantly higher than in the other groups [p: 0.03]. Conclusion: These results showing higher circulating levels of inflammatory cytokines in patients with RLS support the notion that inflammation may be involved in the pathogenesis of primary RLS. However, it is necessary to perform further studies to determine if this finding is a cause or an effect.Publication Metadata only Assessment of atherosclerosis in obese adolescents: Positive correlation of mean platelet volume and carotid intima media thickness(2013-11-01T00:00:00Z) Arslan, Nur; Makay, Balahan; Hizli, Samil; KOÇYİĞİT, ABDÜRRAHİM; Demircioglu, Fatih; Tuncel, Alpaslan Sedat; Cakmakci, Handan; KOÇYİĞİT, ABDÜRRAHİMAims: This study aims to assess the correlation of mean platelet volume (MPV) and common carotid artery (CCA) thickness in a population of obese adolescents.Publication Metadata only Çocukluk çağı kronik idiyopatik ürtikerinde plazma tiyol dengesi ve hastalık ağırlığı ilişkisi(2018-04-23) Dilek, Fatih; ÖZÇEKER, DENİZ; ÖZKAYA, EMİN; GÜLER, ERAY METİN; TAMAY, ZEYNEP ÜLKER; yazıcı, mebrure; KOÇYİĞİT, ABDÜRRAHİM; guler, nermin; ÖZKAYA, EMİN; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİMPublication Metadata only Anti-Cancer Effect Of Urfa Pistachio (Pistacia Vera) Green Hull Extract On Colon Adenocarcinoma Cells(2016-10-30T00:00:00Z) KOYUNCU, İSMAİL; KOÇYİĞİT, ABDÜRRAHİM; Yüksekdağ, Özgür; GÜLER, ERAY METİN; GÖNEL, ATAMAN; KİRMİT, ADNAN; KOÇYİĞİT, ABDÜRRAHİM; GÜLER, ERAY METİNPublication Metadata only Evaluating Cytotoxic Effects and Cytotoxicity Origins of Bulk-Fill Materials by LC-MS/MS.-(2022-09-17T00:00:00Z) Kazak, Mağrur; Dönmez, Nazmiye; Bahadori, Fatemeh; Yenigün, Vildan Betül; Koçyiğit, Abdürrahim; DÖNMEZ, NAZMİYE; YENİGÜN, VILDAN BETÜL; KOÇYİĞİT, ABDÜRRAHİM