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Protoporphyrin IX-loaded magnetoliposomes as a potential drug delivery system for photodynamic therapy: Fabrication, characterization and in vitro study

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Date
2016-03-01
Author
Basoglu, HARUN
Bilgin, Mehmet Dincer
Demir, Mustafa Muammer
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Type
Article
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Abstract
Background: Protoporphyrin IX (PpIX) is a well-known photosensitizer that has great potential for use in photodynamic therapy (PDT). However, aggregation behavior of PpIX in neutral water makes it inappropriate for physiological studies. PpIX-loaded magnetoliposomes (MLs) were fabricated to increase PpIX biocompatibility. PpIX-loaded ML physical properties were characterized, and PpIX-loaded ML drug release behavior was investigated under the influence of an external magnetic field and heat. Toxicity and photodynamic effects of the complex were also examined using in vitro experiments with MCF-7 human breast cancer cells.
Subject
Basoglu H., Bilgin M. D. , Demir M. M. , -Protoporphyrin IX-loaded magnetoliposomes as a potential drug delivery system for photodynamic therapy: Fabrication, characterization and in vitro study-, PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, cilt.13, ss.81-90, 2016
URI
https://hdl.handle.net/20.500.12645/1056
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  • PubMed İndeksli Yayın Koleksiyonu
  • Scientific and Technological Research Council of Turkey
  • Scopus İndeksli Yayınlar Koleksiyonu
  • WoS İndeksli Yayınlar Koleksiyonu
  • Yayınlar - Eserler

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BEZMIALEM VAKIF UNIVERSITY

About us |Policies | Library | Contact us | Send Feedback | Sitemap | Admin

Bezmialem Vakıf Üniversitesi, Adnan Menderes Bulvarı Vatan Caddesi 34093 Fatih, İstanbul / TURKEY
Copyright © Bezmialem Vakıf Üniversitesi

Creative Commons Lisansı
Bezmialem Institutional Repository, Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

OpenAccess@BVU

Support by  UNIREPOS