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Protoporphyrin IX-loaded magnetoliposomes as a potential drug delivery system for photodynamic therapy: Fabrication, characterization and in vitro study

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dc.contributor.authorBasoglu, HARUN
dc.contributor.authorBilgin, Mehmet Dincer
dc.contributor.authorDemir, Mustafa Muammer
dc.contributor.institutionauthorBAŞOĞLU, HARUN
dc.date.accessioned2019-10-05T12:57:59Z
dc.date.available2019-10-05T12:57:59Z
dc.date.issued2016-03-01
dc.description.abstractBackground: Protoporphyrin IX (PpIX) is a well-known photosensitizer that has great potential for use in photodynamic therapy (PDT). However, aggregation behavior of PpIX in neutral water makes it inappropriate for physiological studies. PpIX-loaded magnetoliposomes (MLs) were fabricated to increase PpIX biocompatibility. PpIX-loaded ML physical properties were characterized, and PpIX-loaded ML drug release behavior was investigated under the influence of an external magnetic field and heat. Toxicity and photodynamic effects of the complex were also examined using in vitro experiments with MCF-7 human breast cancer cells.
dc.description.sponsorshipTürkiye Bilimsel Ve Teknolojik Araştırma Kurumu ( Tubitak )
dc.identifier10.1007/s00404-009-1330-7
dc.identifier.citationBasoglu H., Bilgin M. D. , Demir M. M. , -Protoporphyrin IX-loaded magnetoliposomes as a potential drug delivery system for photodynamic therapy: Fabrication, characterization and in vitro study-, PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, cilt.13, ss.81-90, 2016
dc.identifier.doi10.1016/j.pdpdt.2015.12.010
dc.identifier.pubmed26751701
dc.identifier.scopus84960473615
dc.identifier.urihttps://hdl.handle.net/20.500.12645/1056
dc.identifier.wosWOS:000372376500013
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleProtoporphyrin IX-loaded magnetoliposomes as a potential drug delivery system for photodynamic therapy: Fabrication, characterization and in vitro study
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameArchives of gynecology and obstetrics
local.avesis.id18b1c61c-31f1-4693-9d75-45e00403e9b1
local.avesis.response926
local.indexed.atPubMed
local.indexed.atWOS
local.indexed.atScopus
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
local.publication.isinternational1
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relation.isAuthorOfPublication.latestForDiscoveryedc8a4e9-2246-481d-b366-a36d4acf3dcb
relation.isGoalOfPublication9c198c48-b603-4e2f-8366-04edcfc1224c
relation.isGoalOfPublication.latestForDiscovery9c198c48-b603-4e2f-8366-04edcfc1224c

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