The structural basis of the social economy is non-profit organizations. Therefore, understanding the structure and management principles of non-profits is essential to create a global economy based on solidarity. However, despite the critical importance and role of non-profit organizations, studies on non-profit organizations are not holistic from a managerial perspective. For this reason, a holistic approach that covers all economic, political, and social components is needed when analyzing the social economy and NPOs Toward this aim, in this section, nonprofits are examined based on their organizational structure and management principles. This examination will compare for-profit and non-profits organizations’ mission, organizational structure, performance criteria, etc. The lack of profit in non-profit organization’s (NPO) mission stands out as the most crucial difference that shapes their management characteristics and organizational structure.Keywords: Social Organizations, Social Economy, Organizational Structure, Non-profit Organizations