Publication:
Acute kidney injury in Turkey: epidemiological characteristics, etiology, clinical course, and prognosis

Loading...
Thumbnail Image
Date
2022-10-01T00:00:00Z
Authors
GÜRSU, Meltem
Yegenaga, Itir
TUĞLULAR, ZÜBEYDE SERHAN
DURSUN, BELDA
GÖKÇAY BEK, SİBEL
Bardak, Simge
ONAN, ENGİN
Demir, Serap
DERİCİ, ÜLVER
DOĞUKAN, AYHAN
Journal Title
Journal ISSN
Volume Title
Publisher
Research Projects
Organizational Units
Journal Issue

Metrics

Search on Google Scholar

Abstract
Background: This study aimed to evaluate the etiologies, comorbidities, and outcomes of acute kidney injury (AKI) in Turkey and determine any potential differences among different geographical parts of the country. Methods: This prospective observational study was conducted by the Acute Kidney Injury Working Group of the Turkish Society of Nephrology. Demographical and clinical data of patients with AKI at the time of diagnosis and at the 1st week and 1st, 3rd, and 6th months of diagnosis were evaluated to determine patient and renal survival and factors associated with patient prognosis. Results: A total of 776 patients were included (54.7% male, median age: 67 years). Prerenal etiologies, including dehydration, heart failure, and sepsis, were more frequent than other etiologies. 58.9% of the patients had at least one renal etiology, with nephrotoxic agent exposure as the most common etiology. The etiologic factors were mostly similar throughout the country. 33.6% of the patients needed kidney replacement therapy. At the 6th month of diagnosis, 29.5% of the patients had complete recovery; 34.1% had partial recovery; 9.5% developed end-stage kidney disease; and 24.1% died. The mortality rate was higher in the patients from the Eastern Anatolian region; those admitted to the intensive care unit; those with prerenal, renal, and postrenal etiologies together, stage 3 AKI, sepsis, cirrhosis, heart failure, and malignancy; those who need kidney replacement therapy; and those without chronic kidney disease than in the other patients. Conclusion: Physicians managing patients with AKI should be alert against dehydration, heart failure, sepsis, and nephrotoxic agent exposure. Understanding the characteristics and outcomes of patients with AKI in their countries would help prevent AKI and improve treatment strategies.
Description
Keywords
Acute kidney injury, Etiology, Kidney replacement therapy, Survival
Citation
GÜRSU M., Yegenaga I., TUĞLULAR Z. S. , DURSUN B., GÖKÇAY BEK S., Bardak S., ONAN E., Demir S., DERİCİ Ü., DOĞUKAN A., et al., -Acute kidney injury in Turkey: epidemiological characteristics, etiology, clinical course, and prognosis-, BMC NEPHROLOGY, cilt.23, sa.1, 2022
Page Views

7

File Downloads

2

Sustainable Development Goals