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The Effect of Serum Bone Sialoprotein Levels on Tympanosclerosis

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dc.contributor.authorBaki, Ahmet
dc.contributor.authorYildiz, Muhammet
dc.contributor.authorÖZER, Ömer Faruk
dc.contributor.authorÇAĞLAR, Hifa Gülru
dc.contributor.institutionauthorÖZER, ÖMER FARUK
dc.contributor.institutionauthorÇAĞLAR, HİFA GÜLRU
dc.date.accessioned2020-09-01T21:00:12Z
dc.date.available2020-09-01T21:00:12Z
dc.date.issued2020-07-01T00:00:00Z
dc.description.abstractObjective: This study aimed to investigate serum bone sialoprotein (BSP) levels in patients with tympanosclerosis (TS). Methods: We included into this study 24 patients with TS and 24 asymptomatic healthy volunteers. Our study consisted of two groups: TS group (n=24), comprising of patients who underwent surgery for chronic otitis media and had tympanosclerotic plaques; and a control group (n=24), comprising of healthy individuals without ear problems. The serum BSP levels were measured and the results were compared between the two groups. Results: In the TS group, there were 15 female and nine male patients. The ages of the females ranged from 24 to 54 years, while those of the males ranged from 34 to 55 years; the average age was 40.46 +/- 9.75 and 43.11 +/- 6.77, respectively. In the control group, there were 14 females and ten males. The ages of the females ranged from 30 to 48 years, while those of the males ranged from 27 to 47 years; the average age was 40.25 +/- 5.28 and 38.4 +/- 27.08, respectively. There was a statistically significant difference in BSP levels between the two groups (p=0.001). In addition, there was a moderate positive correlation between BSP and hearing levels. Conclusion: The serum BSP levels were higher in the TS group than in the control group and might have some effect on TS. Further studies on a large number of subjects using serum and tissue BSP levels should be designed to affirm the effects of BSP on TS.en
dc.identifier.citationBaki A, Yıldız M, Özer ÖF, Çağlar HG. The Effect of Serum Bone Sialoprotein Levels on Tympanosclerosis. Bezmialem Science 2020;8(3):264-8.
dc.identifier.doi10.14235/bas.galenos.2019.3457
dc.identifier.trdizin376432
dc.identifier.urihttp://hdl.handle.net/20.500.12645/18534
dc.identifier.wosWOS:000560708100010
dc.language.isoen
dc.subjectTimpanosclerosis
dc.subjectbone sialoprotein
dc.subjectcalcification
dc.titleThe Effect of Serum Bone Sialoprotein Levels on Tympanosclerosis
dc.typeArticle
dspace.entity.typePublication
local.avesis.id74fe2f63-5907-499c-bb69-4f54ed516710
local.publication.isinternational1
relation.isAuthorOfPublicationf5267834-a664-4da6-89f3-ae19762e1423
relation.isAuthorOfPublication8f555329-3b57-4441-b23e-6354c76894af
relation.isAuthorOfPublication.latestForDiscovery8f555329-3b57-4441-b23e-6354c76894af
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