Publication:
Saponins from Twenty-Two Cephalaria Species

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Date
2021-11-01T00:00:00Z
Authors
Sarikahya, Nazli Boke
GÖREN, AHMET CEYHAN
Okkali, Gaye Sumer
Kirmizigul, Suheyla
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Research Projects
Sustainable Development Goals
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Abstract
Saponins in the Cephalaria species have a broad spectrum of biological properties and application potentials. This research aimed to develop a novel method to tentatively identify and quantify triterpenes and saponins in 22 Cephalaria species by LC-HR/MS method. In this study, we provided a broad screening of important biologically active triterpenes and saponins with high separation ability, high sensitivity and high selectivity. This is the first report to prove that Cephalaria species can be a good source of tormentic acid which has many biological activities in literature. The main triterpene compound, tormentic acid was presented at the level between 74.02 mg/kg and 75702.0 mg/kg in n-butanol extract of Cephalaria species. The source of some biologically active saponins such as davisianoside B, aristatoside C, elmalienoside A, balansoide B and scoposide B were also determined with this study, for the first time. Therefore, due to the different activities and usages of the identified compounds, these findings may find application in a number of industries such as nutraceutical, pharmaceutical, medical and cosmetic industries.
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Sarikahya N. B. , GÖREN A. C. , Okkali G. S. , Kirmizigul S., -Saponins from Twenty-Two Cephalaria Species-, RECORDS OF NATURAL PRODUCTS, cilt.15, sa.6, ss.537-546, 2021