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Saponins from Twenty-Two Cephalaria Species

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dc.contributor.authorSarikahya, Nazli Boke
dc.contributor.authorGÖREN, AHMET CEYHAN
dc.contributor.authorOkkali, Gaye Sumer
dc.contributor.authorKirmizigul, Suheyla
dc.contributor.institutionauthorGÖREN, AHMET CEYHAN
dc.date.accessioned2021-06-21T20:59:05Z
dc.date.available2021-06-21T20:59:05Z
dc.date.issued2021-11-01T00:00:00Z
dc.description.abstractSaponins in the Cephalaria species have a broad spectrum of biological properties and application potentials. This research aimed to develop a novel method to tentatively identify and quantify triterpenes and saponins in 22 Cephalaria species by LC-HR/MS method. In this study, we provided a broad screening of important biologically active triterpenes and saponins with high separation ability, high sensitivity and high selectivity. This is the first report to prove that Cephalaria species can be a good source of tormentic acid which has many biological activities in literature. The main triterpene compound, tormentic acid was presented at the level between 74.02 mg/kg and 75702.0 mg/kg in n-butanol extract of Cephalaria species. The source of some biologically active saponins such as davisianoside B, aristatoside C, elmalienoside A, balansoide B and scoposide B were also determined with this study, for the first time. Therefore, due to the different activities and usages of the identified compounds, these findings may find application in a number of industries such as nutraceutical, pharmaceutical, medical and cosmetic industries.
dc.identifier.citationSarikahya N. B. , GÖREN A. C. , Okkali G. S. , Kirmizigul S., -Saponins from Twenty-Two Cephalaria Species-, RECORDS OF NATURAL PRODUCTS, cilt.15, sa.6, ss.537-546, 2021
dc.identifier.doi10.25135/rnp.241.21.02.1985
dc.identifier.trdizinISSN: 1307-6167
dc.identifier.trdizinISSN: 1307-6167
dc.identifier.trdizintrdizin
dc.identifier.urihttp://hdl.handle.net/20.500.12645/28992
dc.identifier.wosWOS:000658306500010
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleSaponins from Twenty-Two Cephalaria Species
dc.typeArticle
dspace.entity.typePublication
local.avesis.id5827b23e-970c-4ba0-8e05-ebc358ba7265
local.publication.isinternational1
relation.isAuthorOfPublication07fcea81-8515-4cd4-86f2-047fe6b2df71
relation.isAuthorOfPublication.latestForDiscovery07fcea81-8515-4cd4-86f2-047fe6b2df71
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