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A detailed study on the chemical and biological profiles of essential oil and methanol extract of Thymus nummularius (Anzer tea): Rosmarinic acid

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Date
2015-05-01
Author
Yilmaz, Mustafa Abdullah
Gazioglu, IŞIL
Ertas, Abdulselam
Boga, Mehmet
Yesil, Yeter
Ugurlu, Pelin
Ozturk, Mehmet
Hasimi, Nesrin
Temel, Hamdi
Tel, Gulsen
Advisor
Type
Article
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Abstract
The aim of this study was to determine the chemical profile of Thymus nummularius by LC-MS/MS and GC/MS. Additionally, the methanol extract, essential oil and some individual main compounds of Thymus nummularius were tested for antioxidant, anticholinesterase and antimicrobial activities. Besides, HPLC-FLD was used to determine total aflatoxin in the plant material. Among the twenty-seven compounds studied by LC-MS/MS, rosmarinic acid (131,898.9 +/- 6463.0 mu g/g dry-extract) was found to be the most abundant compound in the methanol extract. On the other hand, thymol (60.38%) and terpinyl-acetate (10.49%) were found to be the major compounds of the essential oil. Both the essential oil and the methanol extract of T. nummularius exhibited strong antioxidant activity in the four tested methods. Furthermore, the essential oil showed high inhibitory activity against acetyl-,butyryl-cholinesterase enzymes and very strong antimicrobial activity against all tested microorganisms. Besides, T. nummularius can be used both as rosmarinic acid source and as food supplement due to its non-aflatoxin content and high antioxidant, anticholinesterase and antimicrobial activities. (C) 2015 Elsevier B.V. All rights reserved.
Subject
Ertas A., Boga M., Yilmaz M. A. , Yesil Y., Tel G., Temel H., Hasimi N., Gazioglu I., Ozturk M., Ugurlu P., -A detailed study on the chemical and biological profiles of essential oil and methanol extract of Thymus nummularius (Anzer tea): Rosmarinic acid-, INDUSTRIAL CROPS AND PRODUCTS, cilt.67, ss.336-345, 2015
URI
https://hdl.handle.net/20.500.12645/8878
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BEZMIALEM VAKIF UNIVERSITY

About us |Policies | Library | Contact us | Send Feedback | Sitemap | Admin

Bezmialem Vakıf Üniversitesi, Adnan Menderes Bulvarı Vatan Caddesi 34093 Fatih, İstanbul / TURKEY
Copyright © Bezmialem Vakıf Üniversitesi

Creative Commons Lisansı
Bezmialem Institutional Repository, Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

OpenAccess@BVU

Support by  UNIREPOS