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A detailed study on the chemical and biological profiles of essential oil and methanol extract of Thymus nummularius (Anzer tea): Rosmarinic acid

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dc.contributor.authorErtas, Abdulselam
dc.contributor.authorBoga, Mehmet
dc.contributor.authorYilmaz, Mustafa Abdullah
dc.contributor.authorYesil, Yeter
dc.contributor.authorTel, Gulsen
dc.contributor.authorTemel, Hamdi
dc.contributor.authorHasimi, Nesrin
dc.contributor.authorGazioglu, IŞIL
dc.contributor.authorOzturk, Mehmet
dc.contributor.authorUgurlu, Pelin
dc.contributor.institutionauthorGAZİOĞLU, IŞIL
dc.date.accessioned2019-10-05T22:05:28Z
dc.date.available2019-10-05T22:05:28Z
dc.date.issued2015-05-01
dc.description.abstractThe aim of this study was to determine the chemical profile of Thymus nummularius by LC-MS/MS and GC/MS. Additionally, the methanol extract, essential oil and some individual main compounds of Thymus nummularius were tested for antioxidant, anticholinesterase and antimicrobial activities. Besides, HPLC-FLD was used to determine total aflatoxin in the plant material. Among the twenty-seven compounds studied by LC-MS/MS, rosmarinic acid (131,898.9 +/- 6463.0 mu g/g dry-extract) was found to be the most abundant compound in the methanol extract. On the other hand, thymol (60.38%) and terpinyl-acetate (10.49%) were found to be the major compounds of the essential oil. Both the essential oil and the methanol extract of T. nummularius exhibited strong antioxidant activity in the four tested methods. Furthermore, the essential oil showed high inhibitory activity against acetyl-,butyryl-cholinesterase enzymes and very strong antimicrobial activity against all tested microorganisms. Besides, T. nummularius can be used both as rosmarinic acid source and as food supplement due to its non-aflatoxin content and high antioxidant, anticholinesterase and antimicrobial activities. (C) 2015 Elsevier B.V. All rights reserved.
dc.identifier10.1891/1061-3749.26.2.249
dc.identifier.citationErtas A., Boga M., Yilmaz M. A. , Yesil Y., Tel G., Temel H., Hasimi N., Gazioglu I., Ozturk M., Ugurlu P., -A detailed study on the chemical and biological profiles of essential oil and methanol extract of Thymus nummularius (Anzer tea): Rosmarinic acid-, INDUSTRIAL CROPS AND PRODUCTS, cilt.67, ss.336-345, 2015
dc.identifier.urihttps://hdl.handle.net/20.500.12645/8878
dc.language.isoen
dc.titleA detailed study on the chemical and biological profiles of essential oil and methanol extract of Thymus nummularius (Anzer tea): Rosmarinic acid
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameJOURNAL OF NURSING MEASUREMENT
local.avesis.iddcb3912c-5661-4637-8ad7-5af9b0ef8d4e
local.avesis.response8754
relation.isAuthorOfPublication336380d2-70ee-496d-a002-08059f9da500
relation.isAuthorOfPublication.latestForDiscovery336380d2-70ee-496d-a002-08059f9da500
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