Fructose-coated nanoparticles: a promising drug nanocarrier for triple-negative breast cancer therapy
STENZEL, Martina H.
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Fructose transporter GLUT5 is overexpressed in breast cancer cell lines, but not in healthy tissue. Micelles based on fructose, which were found to be low fouling, showed a high uptake by breast cancer cells (MCF-7 and MDA-MB-231 cells), but only negligible uptake by macrophages.