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- PublicationMetadata onlyEvaluation of the effect of intra-articular platelet-rich plasma and hyaluronic acid injections on femoral cartilage thickness in chronic knee osteoarthritis.(2022-12-01) Küçükakkaş O.; Aydin T.; Yurdakul O. V.; YURDAKUL, OZAN VOLKAN
- PublicationMetadata onlySpeech auditory brainstem response in audiological practice: a systematic review(2023-01-01) Başöz Behmen M.; Güner N.; Kuru E.; Bal N.; Gedik Toker Ö.; BAŞÖZ, MELIHA; KURU, ELIF; GEDİK, ÖZGEBackground: Speech-ABR is an auditory brainstem response that evaluates the integrity of the temporal and spectral coding of speech in the upper levels of the brainstem. It reflects the acoustic properties of the stimulus used and consists of seven major waves. Waves V and A represent the onset of the response; wave C transition region; D, E, and F waves periodic region (frequency following response); and wave O reflects the offset of the response.PurposeThe aim of this study is to evaluate the clinical availability of the speech-ABR procedure through a literature review.MethodsLiterature search was conducted in Pubmed, Google Scholar, Scopus and Science Direct databases. Clinical studies of the last 15 years have been included in this review and 60 articles have been reviewed.ResultsAs a result of the articles reviewed, it was seen that most of the studies on speech ABR were conducted with children and young people and generally focused on latency analysis measurements. Most used stimulus is the /da/ syllable.ConclusionsSpeech ABR can objectively measure the auditory cues important for speech recognition and has many clini- cal applications. It can be used as a biomarker for auditory processing disorders, learning disorders, dyslexia, otitis media, hearing loss, language disorders and phonological disorders. S-ABR is an effective procedure that can be used in speech and language evaluations in people with hearing aids or cochlear implant. It may also be of benefit to the aging auditory system\"s ability to encode temporal cues.
- PublicationMetadata onlyEvaluation of Anxiety in Turkish Parents of Newborns with Cleft Palate with or Without Cleft Lip(2023-01-01) SUNAL AKTÜRK E.; ŞEKER E. D.; ÇAPKIN D.; KÜTÜK M. S.; SUNAL AKTÜRK, EZGİ; ŞEKER, ELIF DILARA; ÇAPKIN, DUYGU; KÜTÜK, MEHMET SERDAR© 2023, American Cleft Palate Craniofacial Association.Objective: (1) To compare anxiety between parents of newborns with cleft lip and palate (CLP), isolated cleft palate (CP), and healthy newborns and (2) to evaluate anxiety between parental dyads within these groups. Design: A cross-sectional study. Setting: University Hospital. Participants: Surveys were completed by 20 mothers and 20 fathers of newborns with CLP, 21 mothers and 21 fathers of newborns with CP, and 23 mothers and 23 fathers of healthy newborns (controls). Main Outcome Measure: The State-Trait Anxiety Inventory (STAI) assessed parental anxiety. Mothers of newborns with a cleft reported on concerns regarding cleft-related issues and facial appearance. Results: State and trait anxiety were generally in the moderate range for parents of newborns with a cleft, while control parents had low state anxiety and moderate trait anxiety. Mothers of newborns with CP and CLP had significantly higher state and trait anxiety levels than control mothers (p <.05). Fathers of newborns with CLP had a higher state anxiety level than control fathers. When maternal and paternal anxiety was compared within the groups, only trait anxiety scores were significantly higher in mothers of newborns with CLP than that of fathers (p <.05). More than half of mothers of newborns with a cleft were concerned about their newborn\"s feeding, speech, and palate. Conclusions: Parents of children with a cleft may need psychological support in the early postnatal period. It is important for neonatal cleft team providers to help reduce parental anxiety and educate families about cleft care, with a focus on feeding.
- PublicationMetadata onlyComparison of Cytokine Hemadsorption as an Immunomodulator Therapy in COVID-19 Patients with and without Bacterial Sepsis(2022-10-01) Koc S.; Hanikoglu F.; Dokur M.; Polat Y.; Celebi S.; Koc S. G.; Kupeli I.; UYSAL H.; UYSAL, HARUN© 2022 Verlag Klinisches Labor GmbH. All rights reserved.Background: In this retrospective study, we aimed to compare the laboratory and clinical results of cytokine hemadsorption as an immunomodulation therapy in COVID-19 ICU patients with or without sepsis. Methods: The levels of PCT, CRP, and ferritin were determined as indicators of infection/sepsis; the levels of interleukins (IL-6, IL-8 and IL-10, and TNF-α) were determined as indicators of cytokine storm were compared. APACHE score, SOFA score, and mortality rates were compared for the progression of the disease in 23 COVID-19 patients. Results: The therapy was generally successful in reducing the levels of IL-6, IL-8, IL-10, and TNF-α but the levels measured after the procedure did not differ among the patients with or without sepsis, suggesting that the presence of sepsis did not affect the efficacy and function of the cytokine hemadsorption procedure in COVID-19 patients. All parameters were reduced after the procedure except the levels of PCT and ferritin and mortality rates of patients diagnosed with sepsis. The level of PCT was significantly higher in these patients compared with the patients without sepsis while the ferritin and mortality did not show any significant difference between the two groups, suggesting that the cytokine hemadsorption may be safe in the treatment of critical COVID-19 patients. Conclusions: As a result, the progression of sepsis in COVID-19 may be avoided with cytokine hemadsorption applied as an immunomodulator therapy. However, this therapy should be further explored and validated prior to its introduction to everyday clinical practice when the epidemic conditions end.
- PublicationMetadata onlyThe natural course of non-alcoholic fatty liver disease.(2020-01-20) Seval G. C.; Kabacam G.; Yakut M.; Seven G.; Savas B.; Elhan A.; Cinar K.; Idilman R.; SEVEN, GÜLSEREN