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Parathyroid Allotransplant With a New Technique: A Prospective Clinical Trial.

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43-10.6002-ect.2014.0294.pdf (205.7Kb)
Date
2016-08-01
Author
Kesgin, Toka
ERCAN, C
Aysan, E
MUSLUMANOGLU, M
ALTUG, B
IDIZ, UO
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Article
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Abstract
Objectives: Parathyroid allotransplant is a valuable alternative in treating permanent hypoparathyroidism. However, it is a difficult process that requires several trained staff and advanced laboratory equipment, which makes the costs high. Here, we identify a new parathyroid allotransplant technique. Materials and Methods: After obtaining informed consent from patients, parathyroid cell suspensions obtained from 4 donors who had undergone a subtotal parathyroidectomy owing to chronic renal failure were transplanted in 10 patients with permanent hypoparathyroidism after short-term cell cultivation. Prednisolone were used as immunosuppressant for the first 10 days and discontinued thereafter. Results: Allograft function was observed in 7 patients (70%) at a mean follow-up of 12 months. Daily oral calcium and vitamin D supplementations discontinued totally in 7 patients. No major or minor complication was observed. Conclusions: Our technique is simple, fast, and has a low cost, with a 70% success rate at a mean follow-up of 12 months. It requires few staff, minimal equipment, and short-term immunosuppressant use for main tenance. The technical developments of parathyroid allotransplant, as mentioned in this study, may be important in treating permanent hypoparathyroidism
Subject
Aysan E., ALTUG B., ERCAN C., Kesgin T., IDIZ U., MUSLUMANOGLU M., -Parathyroid Allotransplant With a New Technique: A Prospective Clinical Trial.-, Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, cilt.14, ss.431-5, 2016
URI
https://hdl.handle.net/20.500.12645/4845
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  • Yayınlar - Eserler [9994]

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BEZMIALEM VAKIF UNIVERSITY

About us |Policies | Library | Contact us | Send Feedback | Sitemap | Admin

Bezmialem Vakıf Üniversitesi, Adnan Menderes Bulvarı Vatan Caddesi 34093 Fatih, İstanbul / TURKEY
Copyright © Bezmialem Vakıf Üniversitesi

Creative Commons Lisansı
Bezmialem Institutional Repository, Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

OpenAccess@BVU

Support by  UNIREPOS