Publication:
Parathyroid Allotransplant With a New Technique: A Prospective Clinical Trial.

dc.contributor.authorAysan, E
dc.contributor.authorALTUG, B
dc.contributor.authorERCAN, C
dc.contributor.authorKesgin, Toka
dc.contributor.authorIDIZ, UO
dc.contributor.authorMUSLUMANOGLU, M
dc.contributor.institutionauthorAYŞAN, MUSTAFA ERHAN
dc.contributor.institutionauthorERCAN, ÇİLEM
dc.date.accessioned2019-10-05T14:50:36Z
dc.date.available2019-10-05T14:50:36Z
dc.date.issued2016-08-01
dc.description.abstractObjectives: Parathyroid allotransplant is a valuable alternative in treating permanent hypoparathyroidism. However, it is a difficult process that requires several trained staff and advanced laboratory equipment, which makes the costs high. Here, we identify a new parathyroid allotransplant technique. Materials and Methods: After obtaining informed consent from patients, parathyroid cell suspensions obtained from 4 donors who had undergone a subtotal parathyroidectomy owing to chronic renal failure were transplanted in 10 patients with permanent hypoparathyroidism after short-term cell cultivation. Prednisolone were used as immunosuppressant for the first 10 days and discontinued thereafter. Results: Allograft function was observed in 7 patients (70%) at a mean follow-up of 12 months. Daily oral calcium and vitamin D supplementations discontinued totally in 7 patients. No major or minor complication was observed. Conclusions: Our technique is simple, fast, and has a low cost, with a 70% success rate at a mean follow-up of 12 months. It requires few staff, minimal equipment, and short-term immunosuppressant use for main tenance. The technical developments of parathyroid allotransplant, as mentioned in this study, may be important in treating permanent hypoparathyroidismen
dc.identifier10.1007/s00044-015-1424-7
dc.identifier.citationAysan E., ALTUG B., ERCAN C., Kesgin T., IDIZ U., MUSLUMANOGLU M., -Parathyroid Allotransplant With a New Technique: A Prospective Clinical Trial.-, Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, cilt.14, ss.431-5, 2016
dc.identifier.doi10.6002/ect.2014.0294
dc.identifier.pubmed26375142
dc.identifier.scopus84982914013
dc.identifier.urihttps://hdl.handle.net/20.500.12645/4845
dc.identifier.wosWOS:000392952000012
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.titleParathyroid Allotransplant With a New Technique: A Prospective Clinical Trial.
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameMEDICINAL CHEMISTRY RESEARCH
local.avesis.id7704e291-dd1b-446a-b393-03cf78d338c7
local.avesis.response4715
local.publication.isinternational1
relation.isAuthorOfPublication886ea820-98fa-449a-8b4b-26efeff939d8
relation.isAuthorOfPublication4b62f88a-cbba-4426-b872-f37090254c3b
relation.isAuthorOfPublication.latestForDiscovery886ea820-98fa-449a-8b4b-26efeff939d8
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