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dc.contributor.authorAcikgoz, NUSRET
dc.contributor.authorKurtoglu, Ertugrul
dc.contributor.authorYagmur, Julide
dc.contributor.authorKAPICIOĞLU, YELDA
dc.contributor.authorCANSEL, MEHMET
dc.contributor.authorERMİŞ, NECİP
dc.date.accessioned2021-02-09T20:59:22Z
dc.date.available2021-02-09T20:59:22Z
dc.date.issued2018-01-01T00:00:00Z
dc.identifier.urihttp://hdl.handle.net/20.500.12645/28390
dc.description.abstractBehcet disease (BD) is a multisystemic disorder characterized by endothelial dysfunction and inflammation. Monocyte to high-density lipoprotein cholesterol ratio (MHR) is a recently emerged indicator of inflammation and oxidative stress. Sixty patients with BD and 50 control individuals were included to investigate the relationship between MHR and endothelial dysfunction. Endothelial function was assessed by flow- and nitroglycerin-mediated dilatation technique (FMD and NMD, respectively). Serum high-sensitivity C-reactive protein (hsCRP) levels were measured in all study participants. The MHR and hsCRP levels were significantly higher in patients with active BD than in controls. Brachial artery FMD was significantly lower in patients with active BD than in controls. Brachial artery NMD was similar between groups. There was a strong inverse correlation between MHR and FMD and a strong positive correlation between MHR and serum hsCRP levels. Thus, elevated MHR may be a useful marker reflecting impaired endothelial function and systemic inflammation in patients with BD.
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectAcikgoz N., Kurtoglu E., Yagmur J., KAPICIOĞLU Y., CANSEL M., ERMİŞ N., -Elevated Monocyte to High-Density Lipoprotein Cholesterol Ratio and Endothelial Dysfunction in Behcet Disease-, ANGIOLOGY, cilt.69, ss.65-70, 2018
dc.titleElevated Monocyte to High-Density Lipoprotein Cholesterol Ratio and Endothelial Dysfunction in Behcet Disease
dc.typeArticle
dc.identifier.wosWOS:000417677800011
dc.identifier.scopus85043335967
dc.identifier.doi10.1177/0003319717704748
dc.identifier.pubmed28421814
local.publication.isinternational1
dc.contributor.institutionauthorAÇIKGÖZ, NUSRET


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