Show simple item record

dc.contributor.authorEsrefoglu, MUKADDES
dc.date.accessioned2019-10-05T12:39:12Z
dc.date.available2019-10-05T12:39:12Z
dc.date.issued2013-10-28
dc.identifier10.1097/spv.0000000000000407
dc.identifier.citationEsrefoglu M., -Role of stem cells in repair of liver injury: experimental and clinical benefit of transferred stem cells on liver failure.-, World journal of gastroenterology, cilt.19, ss.6757-73, 2013
dc.identifier.urihttps://hdl.handle.net/20.500.12645/277
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812475/
dc.description.abstractAlthough the liver has a high regenerative capacity, as a result of massive hepatocyte death, liver failure occurs. In addition to liver failure, for acute, chronic and hereditary diseases of the liver, cell transplantation therapies can stimulate regeneration or at least ensure sufficient function until liver transplantation can be performed. The lack of donor organs and the risks of rejection have prompted extensive experimental and clinical research in the field of cellular transplantation. Transplantation of cell lineages involved in liver regeneration, including mature hepatocytes, fetal hepatocytes, fetal liver progenitor cells, fetal stem cells, hepatic progenitor cells, hepatic stem cells, mesenchymal stem cells, hematopoietic stem cells, and peripheral blood and umbilical cord blood stem cells, have been found to be beneficial in the treatment of liver failure. In this article, the results of experimental and clinical cell transplantation trials for liver failure are reviewed, with an emphasis on regeneration. © 2013 Baishideng. All rights reserved. Key words: Liver regeneration; Liver failure; Stem cell Core tip: Although the liver has a high regenerative capacity, as a result of massive hepatocyte death, liver failure occurs. In recent years, there has been extensive experimental and clinical research in the field of cellular transplantation. Transplantation of cell lineages involved in liver regeneration, including mature and fetal hepatocytes, fetal liver progenitor and stem cells, hepatic progenitor and stem cells, mesenchymal stem cells, hematopoietic stem cells, and peripheral blood and umbilical cord blood stem cells, have been found to be beneficial for treating of liver failure. Herein, I review the results of experimental and clinical cell transplantation trials for liver failure.en
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.subjectLiver regeneration
dc.subjectLiver failure
dc.subjectStem cell
dc.titleRole of stem cells in repair of liver injury: experimental and clinical benefit of transferred stem cells on liver failure.
dc.typeArticle
local.avesis.response147
local.article.journalnameFEMALE PELVIC MEDICINE AND RECONSTRUCTIVE SURGERY
local.org.facultyTıp Fakültesi
dc.identifier.wosWOS:000326275100008
dc.identifier.scopus84886997357
dc.identifier.doi10.3748/wjg.v19.i40.6757
dc.identifier.pubmed24187451
local.publication.isinternational1


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record