Publication: Relationship between the corpus callosum and neurocognitive disabilities in children with NF-1: diffusion tensor imaging features
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Date
2016-11-01
Authors
Aydin, SİNEM
Kurtcan, SERPİL
Alkan, ALPAY
GULER, Serhat
FILIZ, Mekiya
YILMAZ, TEMEL FATİH
SAHIN, Turkan Uygur
Aralasmak, AYŞE
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Abstract
Purpose: Mild neurocognitive disabilities are commonly observed in children with neurofibromatosis type 1 (NF-1). Enlargement of the corpus callosum (CC) is one of the findings in NF-1, but the pathogenesis has not yet been clarified. In this study, we investigated whether diffusion tensor imaging (DTI) features of CC differed between children with NF-1 and healthy control subjects, and we tried to evahlate the association between the microstructural integrity of CC and neurocognitive disabilities, based on apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values.
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Aydin S., Kurtcan S., Alkan A., GULER S., FILIZ M., YILMAZ T. F. , SAHIN T. U. , Aralasmak A., -Relationship between the corpus callosum and neurocognitive disabilities in children with NF-1: diffusion tensor imaging features-, CLINICAL IMAGING, cilt.40, ss.1092-1095, 2016