Person: KURTCAN, SERPİL
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Publication Evaluation of CSF flow metrics in patients with communicating hydrocephalus and idiopathic intracranial hypertension(2019-05-01) Yilmaz, TEMEL FATİH; Aralasmak, AYŞE; Toprak, HÜSEYİN; MEHDI, Elnur; KOCAMAN, Gulsen; Kurtcan, SERPİL; Kaya, MEHMET ONUR; Alkan, ALPAY; YILMAZ, TEMEL FATİH; ARALAŞMAK, AYŞE; TOPRAK, HÜSEYİN; KURTCAN, SERPİL; KAYA, MEHMET ONUR; ALKAN, ALPAYPurpose To search for CSF dynamics of idiopathic intracranial hypertension (IIH) and communicating hydrocephalus and any correlation between MRI findings, CSF metrics and CSF opening pressure in IIH.Publication Auditory Pathway Features Determined by DTI in Subjects with Unilateral Acoustic Neuroma(2016-12-01) KURTCAN, SERPİL; Alkan, ALPAY; Kilicarslan, R.; BAKAN, A. A.; TOPRAK, HÜSEYİN; ARALASMAK, AYŞE; AKSOY, FEYZA MÜBERRA; Kocer, A.; KURTCAN, SERPİL; ALKAN, ALPAY; TOPRAK, HÜSEYİN; ARALAŞMAK, AYŞEIn the studies concerning the pathology of the auditory pathway in the vestibulocochlear system, few use advanced neuroimaging applications of magnetic resonance imaging (MRI) such as diffusion tensor imaging (DTI). Those who did use reported DTI changes only at the lateral lemniscus and inferior colliculus level. The aim of our study was to determine diffusion changes in the bilateral auditory pathways of subjects with unilateral acoustic neuroma (AN) and compare them with healthy controls.Publication Co-occurrence of spinal and intracranial tuberculoma in a child with juvenile rheumatoid arthritis(2017-02-01) TİMOÇİN, GİZEM; TOPRAK, HÜSEYİN; KURTCAN, SERPİL; ALKAN, ALPAY; TİMOÇİN, GİZEM; TOPRAK, HÜSEYİN; KURTCAN, SERPİL; ALKAN, ALPAYPublication Orucun beyin üzerindeki mikroyapısal etkisinin difüzyon tensör görüntüleme ile değerlendirilmesi(2014-11-16) BAKAN, AYŞE AHSEN; YILDIZ, ŞEYMA; ALKAN, ALPAY; YETİŞ, HÜSEYİN; KURTCAN, SERPİL; İLHAN, MAHMUT MUZAFFER; YILDIZ, ŞEYMA; ALKAN, ALPAY; KURTCAN, SERPİL; İLHAN, MAHMUT MUZAFFERPublication Susceptibility Weighted Imaging Features of Nonketotic Hyperglycemia: Unusual Cause of Hemichorea-Hemiballismus(2015-03-01) ATAY, Musa; YETIS, Huseyin; Kurtcan, SERPİL; Aralasmak, AYŞE; Alkan, ALPAY; KURTCAN, SERPİL; ARALAŞMAK, AYŞE; ALKAN, ALPAYNonketotic hyperglycemia has been described as a metabolic cause of Hemiballism-hemichorea (HB-HC), especially in elderly patients with poorly controlled diabetes. Pathophysiology is not known yet. MRI features tend to be hyperintense in the putamen on T1-weighted images. We present conventional MRI with diffusion weighted imaging (DWI) and susceptibility weighted imaging (SWI) features of two cases with nonketotic hyperglycemia. T1 hyperintensity without diffusion restriction on DWI and minimal putaminal hypointensity without phase shift on SWI were compatible with either pathological mineralization or petechial microhemorrhage or protein denaturation. In the type 2 diabetic patients with HC-HB, conventional MRI together with SWI and DWI will guide to clinician to plan treatment approach.Publication Reversible Corpus Callosum Splenial Lesion Due to Steroid Therapy(2015-05-01) AKSU, Banu; Kurtcan, SERPİL; Alkan, ALPAY; Aralasmak, AYŞE; OKTEM, Faruk; KURTCAN, SERPİL; ALKAN, ALPAY; ARALAŞMAK, AYŞEReversible corpus callosum splenial (CCS) lesions are rare findings and usually detected incidentally. We presented a case of 15-year-old boy with a diagnoses of nephrotic syndrome. He was referred for neuropsychiatric symptoms following dose reduction on steroid treatment. Brain magnetic resonance imaging (MRI) revealed a focal lesion in the CCS, hyperintense on T2 and FLAIR and hypointense on T1 images with diffusion restriction on apparent diffusion coefficient map. Follow-up MRI 3 weeks later showed complete resolution of the lesion. It was probably result of focal intramyelinic edema due to excytotoxic mechanisms and/or arginine-vasopressin release.Publication Diffusion tensor imaging findings of the brainstem in subjects with tonsillar ectopia(2018-03-01) Kurtcan, SERPİL; Alkan, ALPAY; YETIS, Huseyin; TÜZÜN, Umit; Aralasmak, AYŞE; Toprak, HÜSEYİN; Ozdemir, HÜSEYİN; KURTCAN, SERPİL; ALKAN, ALPAY; ARALAŞMAK, AYŞE; TOPRAK, HÜSEYİN; ÖZDEMİR, HÜSEYINWe aimed to evaluate the differences between apparent diffusion coefficient (ADC), fractional anisotropy (FA), axial diffusivity (AD), and radial diffusivity (RD) values obtained from different cranial sites in subjects with Chiari I Malformation (CM-I) and borderline tonsillar ectopia (BTE), and to determine correlations between diffusion tensor imaging (DTI) metrics and the severity of tonsillar ectopia. A total of 73 subjects with CM-I and BTE and 35 control underwent MRI and DTI. In our study, ADC values measured from the level of medulla oblongata and the RD values measured in middle cerebellar peduncles, thalamus, and globus pallidus were higher in CM-I patients than in controls. FA values at the medulla oblongata level and AD values at the medulla oblongata and pons level higher in patients with CM-I. ADC and AD values measured at the pons level were higher in BTE subjects than in controls. Compared with BTE, the CM-I subjects- ADC values at the medulla oblongata and AD values at the pons level were higher. In addition, FAs at the pons and medulla oblongata level were higher. At the medulla oblongata level, a positive correlation was observed between ADC and the size of tonsillar ectopia. AD and FA values measured at the level of medulla oblongata and pons were positively correlated with the size of tonsillar ectopia. These findings may be related to the severity of microstructural changes involving neuronal tracts at the brainstem level due to tonsillar ectopia. DTI may be useful in determining the extent of microstructural changes at the tissue level in subjects with tonsillar ectopia.Publication Craniocervical Dissections: Radiologic Findings, Pitfalls, Mimicking Diseases: A Pictorial Review(2018-01-01) MEHDI, Elnur; Aralasmak, AYŞE; Toprak, HÜSEYİN; Yildiz, Seyma; Kurtcan, SERPİL; Kolukisa, MEHMET; Asil, TALİP; Alkan, ALPAY; ARALAŞMAK, AYŞE; TOPRAK, HÜSEYİN; YILDIZ, ŞEYMA; KURTCAN, SERPİL; KOLUKISA, MEHMET; ASİL, TALIP; ALKAN, ALPAYBackground: Craniocervical Dissections (CCD) are a crucial emergency state causing 20% of strokes in patients under the age of 45. Although DSA (digital substraction angiography) is regarded as the gold standard, noninvasive methods of CT, CTA and MRI, MRA are widely used for diagnosis. Aim: Our aim is to illustrate noninvasive imaging findings in CCD. Conclusion: Emphasizing on diagnostic pitfalls, limitations and mimicking diseases.Publication Malignite ile karışabilen agresif spinal hemanjiom(2015-05-09T00:00:00Z) KURTCAN, SERPİL; ALKAN, ALPAY; GÜLER, SERHAT; YILMAZ, TEMEL FATİH; YILMAZBAYHAN, EMİNE DİLEK; KURTCAN, SERPİL; ALKAN, ALPAY; YILMAZ, TEMEL FATİHPublication Relationship between the corpus callosum and neurocognitive disabilities in children with NF-1: diffusion tensor imaging features(2016-11-01) Aydin, SİNEM; Kurtcan, SERPİL; Alkan, ALPAY; GULER, Serhat; FILIZ, Mekiya; YILMAZ, TEMEL FATİH; SAHIN, Turkan Uygur; Aralasmak, AYŞE; AYDIN, SİNEM; KURTCAN, SERPİL; ALKAN, ALPAY; YILMAZ, TEMEL FATİH; ARALAŞMAK, AYŞEPurpose: Mild neurocognitive disabilities are commonly observed in children with neurofibromatosis type 1 (NF-1). Enlargement of the corpus callosum (CC) is one of the findings in NF-1, but the pathogenesis has not yet been clarified. In this study, we investigated whether diffusion tensor imaging (DTI) features of CC differed between children with NF-1 and healthy control subjects, and we tried to evahlate the association between the microstructural integrity of CC and neurocognitive disabilities, based on apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values.
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