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CHARACTERISTICS AND SURVIVAL RESULTS OF PERITONEAL DIALYSIS PATIENTS SUFFERING FROM COVID-19 IN TURKEY: A MULTICENTER NATIONAL STUDY

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2022-11-01

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GÜRSU M.
ÖZTÜRK S.
ARICI M.
Sahin I.
Goekcay Bek S.
Yilmaz M.
Koyuncu S.
Karahisar Sirali S.
Ural Z.
Dursun B.

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Abstract

Background: We aimed to study the characteristics of peritoneal dialysis (PD) patients with Coronavirus disease-19 (COVID-19), determine the short-term mortality and other medical complications, and delineate the factors associated with COVID-19 outcome.Methods: In this multicenter national study, we included PD patients with confirmed COVID-19 from 27 centers. The baseline demographic, clinical, laboratory, and radiological data and outcomes at the end of the first month were recorded.Results: We enrolled 142 COVID-19 patients (median age:52 years). 58.2% of patients had mild disease at diagnosis. Lung involvement was detected in 60.8% of patients. 83 (58.4%) patients were hospitalized, 31 (21.8%) patients were admitted to intensive care unit and 24 needed mechanical ventilation. 15 (10.5%) patients were switched to hemodialysis and hemodiafiltration was performed for four (2.8%) patients. Persisting pulmonary symptoms (n=27), lower respiratory system infection (n=12), rehospitalization for any reason (n=24), malnutrition (n=6), hypervolemia (n=13), peritonitis (n=7), ultrafiltration failure (n=7) and in PD modality change (n=8) were reported in survivors. 26 patients (18.31%) died in the first month of diagnosis. The non-survivor group was older, comorbidities were more prevalent. Fever, dyspnea, cough, serious-vital disease at presentation, bilateral pulmonary involvement, and pleural effusion were more frequent among non-survivors. Age (OR:1.102; 95%CI: 1.032-1.117; p: 0.004), moderate-severe clinical disease at presentation (OR:26.825; 95%CI: 4.578-157.172; p<0.001) and baseline CRP (OR:1.008; 95%CI; 1.000-1.016; p:0.040) were associated with first-month mortality in multivariate analysis.Conclusions: Early mortality rate and medical complications are quite high in PD patients with COVID-19. Age, clinical severity of COVID-19, and baseline CRP level are the independent parameters associated with mortality.

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Tıp, Dahili Tıp Bilimleri, İç Hastalıkları, Nefroloji, Yaşam Bilimleri, Sağlık Bilimleri, Temel Tıp Bilimleri, Biyokimya, Fizyoloji, Temel Bilimler, Medicine, Internal Medicine Sciences, Internal Diseases, Nephrology, Life Sciences, Health Sciences, Fundamental Medical Sciences, Biochemistry, Human Physiology, Natural Sciences, FİZYOLOJİ, Biyoloji ve Biyokimya, Yaşam Bilimleri (LIFE), ÜROLOJİ VE NEFROLOJİ, Klinik Tıp, Klinik Tıp (MED), PERİFERİK DAMAR HASTALIKLARI, PHYSIOLOGY, BIOLOGY & BIOCHEMISTRY, Life Sciences (LIFE), UROLOGY & NEPHROLOGY, CLINICAL MEDICINE, Clinical Medicine (MED), PERIPHERAL VASCULAR DISEASE, Üroloji, Fizyoloji (tıbbi), Biyokimya (tıbbi), Urology, Physiology (medical), Biochemistry (medical), Physiology

Citation

GÜRSU M., ÖZTÜRK S., ARICI M., Sahin I., Goekcay Bek S., Yilmaz M., Koyuncu S., Karahisar Sirali S., Ural Z., Dursun B., et al., "CHARACTERISTICS AND SURVIVAL RESULTS OF PERITONEAL DIALYSIS PATIENTS SUFFERING FROM COVID-19 IN TURKEY: A MULTICENTER NATIONAL STUDY", KIDNEY & BLOOD PRESSURE RESEARCH, cilt.47, sa.10, ss.605-615, 2022
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