Publication:
Fulminan karaciğer yetmezliği ile seyreden viral hepatitli olguların değerlendirilmesi

Simple item page
dc.contributor.authorKARABELA, ŞEMSI NUR
dc.contributor.authorŞENOĞLU, SEVTAP
dc.contributor.authorDURDU, BÜLENT
dc.contributor.authorBakar, Mehmet
dc.contributor.authorYAŞAR, KADRIYE KART
dc.contributor.institutionauthorDURDU, BÜLENT
dc.date.accessioned2019-10-05T12:38:23Z
dc.date.available2019-10-05T12:38:23Z
dc.date.issued2016-05-01
dc.description.abstractBackground and Aims: Fulminant hepatic failure, a severe and acute hepatic injury that manifests as a sudden impairment of hepatic synthetic functions and progresses accompanied with encephalopathy in patients with normal hepatic functions, is most commonly caused by viral hepatitis in Turkey. This study analyzed patients with a fulminant clinical course of viral hepatitis followed up in our clinic. Metarial and Methods: Patients with viral hepatitis who were diagnosed with fulminant hepatitis between 1991 and 2012 were retrospectively analyzed. Fulminant hepatic failure that occurred within the first 8 weeks after the onset of the first symptoms and/or failure that occurred within 2 weeks following jaundice was accepted as acute failure, whereas failure that occurred within a longer period was considered as subacute failure. Only demographic data and outcomes of the cases monitored between 1991 and 1997 were available. Results: Twenty-eight (58%) patients were female and 20 were male, and the age range was 15–70 years (mean, 35.3 years). The shortest and longest symptom onset durations were 2 and 21 days, respectively (mean, 7.4 days). Acute cases (80%) were commonly found, and the most common type of viral hepatitis was hepatitis B (39%). Eight patients were negative for hepatitis markers, and they had not taken any drug, plant, or toxic substance (31%); they died on the first day of hospitalization. Twelve (25%) patients with a diagnosis of fulminant hepatitis recovered by supportive therapy. When the distribution of cases by years was analyzed, it was observed that the number of cases significantly decreased as the years progressed. Conclusion: Fulminant hepatitis is a difficult clinical entity to cure and generally progresses to mortality. The mortality rate of the disease can be reduced depending on early diagnosis and treatment with supportive therapy, including intensive care unit treatment and performing hepatic transplantation.en
dc.identifier
dc.identifier.citationKARABELA Ş. N. , ŞENOĞLU S., DURDU B., Bakar M., YAŞAR K. K. , -Fulminan karaciğer yetmezliği ile seyreden viral hepatitli olguların değerlendirilmesi-, Akademik Gastroenteroloji Dergisi, cilt.15, ss.41-44, 2016
dc.identifier.urihttps://hdl.handle.net/20.500.12645/237
dc.language.isotr
dc.titleFulminan karaciğer yetmezliği ile seyreden viral hepatitli olguların değerlendirilmesi
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameTurkiye Klinikleri Cerrahi
local.avesis.id02a28f2d-95a5-4609-9db3-8cb284367877
local.avesis.response107
local.org.facultyTıp Fakültesi
local.publication.isinternational0
relation.isAuthorOfPublication9814f802-a79c-45fd-aa3e-f1ba9d40884b
relation.isAuthorOfPublication.latestForDiscovery9814f802-a79c-45fd-aa3e-f1ba9d40884b
Files
Collections
Yayınlar - Eserler
Tıp Fakültesi