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Do Low Serum UCH-L1 and TDP-43 Levels Indicate Disturbed Ubiquitin-Proteosome System in Autism Spectrum Disorder?

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Cetin, Ihsan
Tezdig, Ihsan
TARAKCLOGLU, Mahmut Cem
Kadak, Muhammed Tayyib
Demirel, Omer Faruk
Ozer, Omer Faruk
Erdogan, Firat
Dogangun, Burak

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Introduction: The mechanism of ubiquitination-related abnormalities causing neural development problems is still unclear. We examined the association between autism and serum transactive response DNAbinding protein-43 (TDP-43) and ubiquitin c-terminal hydrolase-L1 (UCH-L1) levels, both of which are members of the ubiquitinproteosome system.

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Cetin I., Tezdig I., TARAKCLOGLU M. C. , Kadak M. T. , Demirel O. F. , Ozer O. F. , Erdogan F., Dogangun B., -Do Low Serum UCH-L1 and TDP-43 Levels Indicate Disturbed Ubiquitin-Proteosome System in Autism Spectrum Disorder?-, NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, cilt.54, ss.267-271, 2017

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