Person: ÖZER, ÖMER FARUK
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Publication Protective effect of dexpanthenol against nephrotoxic effect of amikacin: An experimental study(2017-05-01) Dogan, ELİF ECE; ERKOC, Reha; EKINCI, Iskender; HAMDARD, Jamshid; DONER, Baris; KARATOPRAK, CUMALİ; Coban, GANİME; Ozer, Omer Faruk; Kazancioglu, RÜMEYZA; DOĞAN, ELİF ECE; KARATOPRAK, CUMALİ; ÇOBAN, GANİME; ÖZER, ÖMER FARUK; KAZANCIOĞLU, RÜMEYZABackground: Amikacin has the largest spectrum among aminoglycosides, its nephrotoxic effect limits its utilization. Our purpose in this study is to review the protective effect of dexpanthenol against the nephrotoxic effect of amikacin, accompanied with histopathological and biochemical parameters.Publication Farelede Radyoterapinin Etkileri(2015-04-27T00:00:00Z) TAŞPINAR, ÖZGÜR; AYDIN, TEOMAN; KILIÇ, GÖKHAN; EREN, FATMA; KIZILTAN, HURİYE; KEPEKÇİ, MÜGE; ERİŞ, HİKMET; KESKİN, YAŞAR; ÖZER, ÖMER FARUK; SELEK, ŞAHBETTİN; SEYİTHANOĞLU, MEHMET HAKAN; AYDIN, TEOMAN; KILIC, GÖKHAN; KESKİN, YAŞAR; ÖZER, ÖMER FARUK; SELEK, ŞAHABETTİNPublication Role of circulating adipocytokines vaspin, apelin, and visfatin in the loss of appetite in underweight children: a pilot trial(2015-09-01) Vehapoglu, AYSEL; USTABAS, Feyza; OZGEN, Tolga I.; Terzioglu, Sule; CERMIK, Banu B.; OZEN, Omer F.; VEHAPOĞLU TÜRKMEN, AYSEL; USTABAŞ KAHRAMAN, FEYZA; ÖZGEN, İLKER TOLGA; TERZİOĞLU, ŞULE; ÖZER, ÖMER FARUKObjectives: To investigate serum concentrations of vaspin, apelin, and visfatin in underweight children and their association with anthropometric and nutritional markers of malnutrition.Publication Oxidative stress in maternal milk and cord blood in gestational diabetes mellitus: a prospective study.(2022-05-01T00:00:00Z) Erdoğan, Fırat; Şenkal, Evrim; Özer, Ömer Faruk; İpek, İlke Özahi; Altuntaş, Şükriye Leyla; Özde, Şükriye; ÖZER, ÖMER FARUKBackground: Reduced antioxidant defenses may reflect a poor protective response against oxidative stress and this may be implicated in progression of gestational diabetes mellitus (GDM). Oxidative stress induced by hyperglycemia plays a major role in micro and macrovascular complications, which imply endothelial dysfunction. Objective: Our aim in this study was to investigate the association between GDM and oxidative stress markers measured in plasma, with regard to revealing changes to total antioxidant capacity (TAC) and total oxidant status (TOS) among mothers showing impairments in oral glucose tolerance tests (OGTTs). Design and setting: Prospective study at a university hospital in Turkey. Methods: The study group consisted of 50 mothers with GDM, and 59 healthy mothers served as controls. Umbilical cord blood samples were taken from all mothers during delivery and breast milk samples on the fifth day after delivery. TAC, TOS, thiol and disulfide levels were measured. Results: No statistically significant relationship between the blood and milk samples could be found. An analysis on correlations between TAC, TOS and certain parameters revealed that there were negative correlations between TOS and total thiol (r = -0.386; P < 0.001) and between TOS and disulfide (r = -0.388; P < 0.001) in milk in the control group. However, these findings were not observed in the study group. Conclusion: Our findings suggested that a compensatory mechanism of oxidative stress was expected to be present in gestational diabetes mellitus and that this might be ameliorated through good glycemic regulation and antioxidant supplementation.Publication Protective effects of silymarin against kidney injury caused by high dose administration of isotretinoin in mice.(2015-09-24) Kumaş, MELTEM; EŞREFOĞLU, MUKADDES; Kesgin, S; Özer, OF; KUMAŞ, MELTEM; EŞREFOĞLU, MUKADDES; ÖZER, ÖMER FARUKPublication Protective and therapeutic effects of pyrrolidine dithiocarbamate in a rat tongue cancer model created experimentally using 4-nitroquinoline 1-oxide.(2020-11-01T00:00:00Z) Doğan, R; Hafız, AM; Gucin, Z; Ozer, OF; Ozturan, O; Yenigun, Alper; DOĞAN, REMZI; GÜCİN, ZÜHAL; ÖZER, ÖMER FARUK; YENİGÜN, ALPER; ÖZTURAN, ORHANPublication Amikasinin nefrotoksik etkisine karşı dekspantenolun koruyucu etkisi: Deneysel bir çalışma(2014-10-26) DOĞAN, ELİF ECE; EKINCI, ISKENDER; HAMDARD, JAMSHID; DONER, BARIS; CIKRIKCIOGLU, MEHMET ALI; KARATOPRAK, CUMALİ; ÇOBAN, GANİME; ÖZER, ÖMER FARUK; KAZANCIOĞLU, RÜMEYZA; DOĞAN, ELİF ECE; KARATOPRAK, CUMALİ; ÇOBAN, GANİME; ÖZER, ÖMER FARUK; KAZANCIOĞLU, RÜMEYZAPublication Bezmialem COVID-19 PANDEMİSİNDE Hastalık / Hastane Yönetimi(2021-10-01T00:00:00Z) Selek, Şahabettin; Özer, Ömer Faruk; ÖZER, ÖMER FARUKPublication Assessment of serum endocan levels in patients with beta-thalassemia minor(2022-02-01T00:00:00Z) Zorlu, Mehmet; Ozer, Ömer Faruk; Karatoprak, Cumali; Kıskaç, Muharrem; Çakırca, Mustafa; ZORLU, MEHMET; ÖZER, ÖMER FARUK; KARATOPRAK, CUMALİObjective: Beta-thalassemia minor is a blood disease caused by a hereditary decrease in beta-globin synthesis, frequently leading to hypochromic microcytic anemia. Formerly called endothelial cell-specific molecule 1, endocan is a proteoglycan released by vascular endothelial cells in many organs. Our aim was to investigate the relationship between the beta-thalassemia minor patients and the healthy control group in terms of serum endocan level. Methods: The study was performed in a total of 80 subjects. They were divided into two groups, the beta-thalassemia minor group (n=40) and the healthy control group (n=40). Serum endocan levels, age, sex, body mass index value, and tobacco use data of these groups were compared. Results: No statistically significant difference was detected between the two groups in terms of age, sex, and body mass index values (p>0.05). Endocan levels were measured to be 206.85±88.1 pg/mL in the beta-thalassemia minor group and 236.1±162.8 pg/mL in the control group with no significant difference between the groups in terms of serum endocan levels (p>0.05). Conclusions: In our study, there was no change in endocan level in beta-thalassemia minor. This might be because serum endocan levels are affected by multi-factorial reasons. Serum endocan levels may be altered secondarily to decreased beta-globin chain, increased sympathetic activity due to anemia, or platelet dysfunction induced by oxidative stress in beta-thalassemia minor. Further multicenter studies involving more patients are necessary to demonstrate this.Publication Oleuropein mide kanserine karşı: Yeni Tedavi Umudu(2018-11-20T00:00:00Z) TÜRKDOĞAN, KÜRŞAD; KOÇYİĞİT, ABDÜRRAHİM; GÜLER, ERAY METİN; ÖZER, ÖMER FARUK; KOÇYİĞİT, ABDÜRRAHİM; GÜLER, ERAY METİN; ÖZER, ÖMER FARUK