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Effects of Gold Nanoparticles on Angiogenesis in A Chick Chorioallantoic Membrane Model

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dc.contributor.authorCırık, Samet
dc.contributor.authorElesad, Musa
dc.contributor.authorBaşar, Ebrar
dc.contributor.authorAksu, Elif
dc.contributor.authorErdem, Muaz
dc.contributor.authorYıldıztekin, Faruk
dc.contributor.authorMenekşe, Sinan
dc.contributor.authorÇelikel, Rıdvan
dc.contributor.authorİpek, Mehmet Yusuf
dc.contributor.authorFermanlı, Orhan
dc.contributor.authorEşrefoğlu, Mukaddes
dc.contributor.institutionauthorEŞREFOĞLU, MUKADDES
dc.date.accessioned2020-11-30T20:59:28Z
dc.date.available2020-11-30T20:59:28Z
dc.date.issued2020-08-01T00:00:00Z
dc.description.abstractObjective: Today, nanotechnology is widely used in many fields because of its ability to alter the structure of molecules at the atomic level. Metallic nanoparticles attracted great attention from researchers because of their unique properties. Based on the notable features of gold nanoparticles (AuNPs), they have long been evaluated as a potential diagnostic tool for several cancers and for drug delivery applications. Angiogenesis is the development of new vessels that support embryonic up growth and critically modulate many biological processes through adulthood. The inhibition of angiogenesis causes regression of development and metastasis of malign tumours. In this study we aim to examine the effects of AuNPs on angiogenesis in an in vivo chick chorioallantoic membrane (CAM) model. Methods: We applied 20 mL concentrations of AuNPs solution to 24 eggs of the CAM on the fifth day. After then, we evaluated results macroscopically on the 6th and 7th days. Results: In our study, we observed that AuNPs induced angiogenesis. Conclusion: We suggest that AuNPs may not be ideal nanoparticles to make biosensors due to increasing angiogenesis during the course of cancers.en
dc.identifier.citationCırık S, Musa Elesad M, Başar E, Aksu E, Erdem M, Yıldıztekin F, Menekşe S, Çelikel R, İpek My, Fermanli O, Eşrefoğlu M. Effects of Gold Nanopartıcles on Angıogenesıs in A Chıck Chorıoallantoıc Membrane Model. Bezmialem Science 2020;8(4):398-402.
dc.identifier.trdizin459045
dc.identifier.urihttp://hdl.handle.net/20.500.12645/27470
dc.identifier.wosWOS:000600293100012
dc.subjectAngiogenesisen
dc.subjectchorioallantoic membraneen
dc.subjectgold nanoparticlesen
dc.subjectcanceren
dc.titleEffects of Gold Nanoparticles on Angiogenesis in A Chick Chorioallantoic Membrane Modelen
dc.typeArticle
dspace.entity.typePublication
local.avesis.idac4fe45e-cf0e-46bb-b434-6b33f86e9777
local.publication.isinternational0
relation.isAuthorOfPublicationd0c7c343-3b7d-47ef-a2a7-5169234110eb
relation.isAuthorOfPublication.latestForDiscoveryd0c7c343-3b7d-47ef-a2a7-5169234110eb
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