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Vaspin and lipocalin-2 levels in severe obsructive sleep apnea.

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dc.contributor.authorKıSKAÇ, MUHARREM
dc.contributor.authorZORLU, MEHMET
dc.contributor.authorAKKOYUNLU, MUHAMMED EMİN
dc.contributor.authorKILIC, ERDEM
dc.contributor.authorCAKIRCA, MUSTAFA
dc.contributor.authorKaratoprak, CUMALİ
dc.contributor.authorYAVUZ, E
dc.contributor.authorARDIC, C
dc.contributor.authorCAMLI, AHMET ADİL
dc.contributor.authorCIKRIKCIOGLU, M
dc.contributor.authorKART, L
dc.contributor.institutionauthorKISKAÇ, MUHARREM
dc.contributor.institutionauthorZORLU, MEHMET
dc.contributor.institutionauthorAKKOYUNLU, MUHAMMED EMİN
dc.contributor.institutionauthorKILIÇ, ERDEM
dc.contributor.institutionauthorKARATOPRAK, CUMALİ
dc.contributor.institutionauthorÇAKIRCA, MUSTAFA
dc.contributor.institutionauthorÇAMLI, AHMET ADİL
dc.date.accessioned2019-10-05T13:31:45Z
dc.date.available2019-10-05T13:31:45Z
dc.date.issued2014-06-01
dc.description.abstractBackground: Vaspin and lipocalin-2 are less-known recent members of adipocytokine family. There are ongoing studies investigating the role of vaspin ve lipocalin-2 in metabolic syndrome (MS). Obstructive sleep apnea syndrome (OSAS) is independently associated with an increased prevalence of MS. We aimed to measure the levels of vaspin and lipocalin-2 which are secreted from adipocytes in patients with severe OSAS and examine the relationship between these two adipocytokines and OSAS. Methods: The study consisted of two groups: severe OSAS patients with an apnea-hypopnea index (AHI) of >30/h (OSAS group, 34 subjects) and age-matched healthy volunteers with a AHI <5/h (control group, 25 subjects) Serum levels of vaspin and lipocalin-2 in these two groups were compared. Results: Serum levels of vaspin were significantly lower in OSAS group; patients with severe OSAS compared with control group; healthy volunteers (OSAS group: 0.69±0.5 vs. control group: 1.24±1.13; P=0.034). The difference between the two groups in terms of serum levels of lipocalin-2 has not reached statistical significance (OSAS group: 61.6±18.2 vs. control group: 68.5±20.1; P=0.17). Conclusions: We found that serum vaspin levels were significantly lower in patients with severe OSAS compared with healthy controls. Lipocalin-2 levels were similar. The decrease in serum vaspin levels in severe OSAS patients may be important in diagnosis and follow-up of these patients.en
dc.identifier10.1055/s-0034-1371715
dc.identifier.citationKıSKAÇ M., ZORLU M., AKKOYUNLU M. E. , KILIC E., Karatoprak C., CAKIRCA M., YAVUZ E., ARDIC C., CAMLI A. A. , CIKRIKCIOGLU M., et al., -Vaspin and lipocalin-2 levels in severe obsructive sleep apnea.-, Journal of thoracic disease, cilt.6, ss.720-5, 2014
dc.identifier.pubmed24976995
dc.identifier.trdizintrdizin
dc.identifier.urihttps://hdl.handle.net/20.500.12645/2302
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.titleVaspin and lipocalin-2 levels in severe obsructive sleep apnea.
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameEuropean Journal of Pediatric Surgery
local.avesis.id37ec7b7a-9b7d-440b-b94e-aea5df192ef1
local.avesis.response2172
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