Publication:
Two New Co(II) Complexes of Picolinate: Synthesis, Crystal Structure, Spectral Characterization, -Glucosidase nhibition and TD/DFT Study

Placeholder

Organizational Units

Program

Authors

Alturk, Suemeyye
Avci, Davut
Kurt, BELMA
Tamer, Omer
Basoglu, Adil
Sonmez, Fatih
Atalay, Yusuf
Dege, Necmi

Advisor

Language

Publisher

Journal Title

Journal ISSN

Volume Title

Abstract

Co(II) complexes of 2-picolinic acid (picH) and 6-methylpyridine-2-carboxylic acid (6-MepicH) {[Co(pic)(2)2H(2)O], (1), [Co(6-Mepic)(pic)2H(2)O], (2)} were obtained and their structural and spectroscopic properties were investigated by XRD, FT-IR and UV-Vis spectroscopic techniques. The measurement of -glucosidase inhibition of the synthesized complex 2 was fulfilled by IC50 values. In order to provide further explanations about the electronic spectral properties, TD-DFT calculations in ethanol solvent and gas phase were carried out. HSEh1PBE/6-311G(d,p) level has been used to calculate the nonlinear optics (NLO) parameters and frontier molecular orbital (FMO) energies. The experimental refractive indexes and optical band gap energies for the Co(II) complexes have been obtained using FT-IR and UV-Vis spectra, respectively. Lastly, the molecular docking study of Co(II) complexes was carried out in order to demonstrate interactions between the synthesized complexes and target protein (the template structure S. cerevisiae isomaltase).

Description

Source:

Keywords:

Keywords

Citation

Alturk S., Avci D., Kurt B., Tamer O., Basoglu A., Sonmez F., Atalay Y., Dege N., -Two New Co(II) Complexes of Picolinate: Synthesis, Crystal Structure, Spectral Characterization, -Glucosidase nhibition and TD/DFT Study-, JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS, cilt.29, ss.1265-1279, 2019

Endorsement

Review

Supplemented By

Referenced By

1

Views

0

Downloads

View PlumX Details


Sustainable Development Goals