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Two New Co(II) Complexes of Picolinate: Synthesis, Crystal Structure, Spectral Characterization, -Glucosidase nhibition and TD/DFT Study

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dc.contributor.authorAlturk, Suemeyye
dc.contributor.authorAvci, Davut
dc.contributor.authorKurt, BELMA
dc.contributor.authorTamer, Omer
dc.contributor.authorBasoglu, Adil
dc.contributor.authorSonmez, Fatih
dc.contributor.authorAtalay, Yusuf
dc.contributor.authorDege, Necmi
dc.contributor.institutionauthorZENGİN KURT, BELMA
dc.date.accessioned2019-10-05T12:58:45Z
dc.date.available2019-10-05T12:58:45Z
dc.date.issued2019-07-01
dc.description.abstractCo(II) complexes of 2-picolinic acid (picH) and 6-methylpyridine-2-carboxylic acid (6-MepicH) {[Co(pic)(2)2H(2)O], (1), [Co(6-Mepic)(pic)2H(2)O], (2)} were obtained and their structural and spectroscopic properties were investigated by XRD, FT-IR and UV-Vis spectroscopic techniques. The measurement of -glucosidase inhibition of the synthesized complex 2 was fulfilled by IC50 values. In order to provide further explanations about the electronic spectral properties, TD-DFT calculations in ethanol solvent and gas phase were carried out. HSEh1PBE/6-311G(d,p) level has been used to calculate the nonlinear optics (NLO) parameters and frontier molecular orbital (FMO) energies. The experimental refractive indexes and optical band gap energies for the Co(II) complexes have been obtained using FT-IR and UV-Vis spectra, respectively. Lastly, the molecular docking study of Co(II) complexes was carried out in order to demonstrate interactions between the synthesized complexes and target protein (the template structure S. cerevisiae isomaltase).
dc.identifier10.4103/0301-4738.90490
dc.identifier.citationAlturk S., Avci D., Kurt B., Tamer O., Basoglu A., Sonmez F., Atalay Y., Dege N., -Two New Co(II) Complexes of Picolinate: Synthesis, Crystal Structure, Spectral Characterization, -Glucosidase nhibition and TD/DFT Study-, JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS, cilt.29, ss.1265-1279, 2019
dc.identifier.doi10.1007/s10904-019-01090-7
dc.identifier.scopus85060905285
dc.identifier.urihttps://hdl.handle.net/20.500.12645/1091
dc.identifier.wosWOS:000471198700022
dc.language.isoen
dc.titleTwo New Co(II) Complexes of Picolinate: Synthesis, Crystal Structure, Spectral Characterization, -Glucosidase nhibition and TD/DFT Study
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameIndian journal of ophthalmology
local.avesis.id199efc41-837d-41ad-8d02-d906a04a0912
local.avesis.response961
local.publication.isinternational1
relation.isAuthorOfPublication3fd265b5-fdd8-4c56-949b-deb0303c3db7
relation.isAuthorOfPublication.latestForDiscovery3fd265b5-fdd8-4c56-949b-deb0303c3db7
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