Publication:
Serum endocan levels in women with restless legs syndrome.

Simple item page
dc.contributor.authorCELIK, K
dc.contributor.authorÇıKRıKÇıOĞLU, MA
dc.contributor.authorHALAC, G
dc.contributor.authorKILIC, ERDEM
dc.contributor.authorAYHAN, S
dc.contributor.authorOZARAS, N
dc.contributor.authorKaratoprak, CUMALİ
dc.contributor.authorYILDIZ, KEMALETTİN
dc.contributor.authorYILDIZ, RS
dc.contributor.authorZORLU, MEHMET
dc.contributor.authorCAKIRCA, MUSTAFA
dc.contributor.authorKıSKAÇ, MUHARREM
dc.contributor.institutionauthorKILIÇ, ERDEM
dc.contributor.institutionauthorYILDIZ, KEMALETTİN
dc.contributor.institutionauthorZORLU, MEHMET
dc.contributor.institutionauthorKARATOPRAK, CUMALİ
dc.contributor.institutionauthorÇAKIRCA, MUSTAFA
dc.contributor.institutionauthorKISKAÇ, MUHARREM
dc.date.accessioned2019-10-05T14:59:18Z
dc.date.available2019-10-05T14:59:18Z
dc.date.issued2015-11-19
dc.description.abstractBackground: Endocan is a recently introduced marker of endothelial dysfunction. The objective of this study was to compare serum endocan levels in patients with restless legs syndrome (RLS) and control subjects in order to elucidate whether RLS is associated with endothelial dysfunction. Methods: A total of 31 drug naïve female patients with RLS and 31 age- and BMI-matched women were included in the study. Patients with pathological or physiological conditions or with a history of medication use that could potentially influence endothelial functions were excluded, as well as those with alcohol or drug abuse history. The two groups were compared with routine blood tests and serum endocan levels. Results: Patients with RLS had lower serum endocan levels than the controls (P=0.037). There was a negative bivariate correlation between RLS severity score and serum endocan levels (r=-0.406, P=0.023). While white blood cell count was significantly higher in RLS group, 25-hydroxy vitamin D3, vitamin B12, transferrin saturation rate, and HDL-cholesterol were significantly lower. Creatininemia and diastolic blood pressure were also marginally insignificantly lower in RLS group. Due to the presence of differences between two groups in these variables, a linear regression analysis was performed that showed a positive association between endocan and creatininemia (β=0.310, P=0.022), and a negative association between endocan and RLS (β=-0.502, P,0.001). Conclusion: The results of this study seem to suggest that patients with RLS may have better endothelial functions when compared with the general population and that these patients may be better protected against atherosclerosisen
dc.identifier10.1016/j.crvasa.2016.02.002
dc.identifier.citationCELIK K., ÇıKRıKÇıOĞLU M., HALAC G., KILIC E., AYHAN S., OZARAS N., YILDIZ K., YILDIZ R., ZORLU M., Karatoprak C., et al., -Serum endocan levels in women with restless legs syndrome.-, Neuropsychiatric disease and treatment, cilt.11, ss.2919-25, 2015
dc.identifier.doi10.2147/ndt.s92771
dc.identifier.pubmed26640378
dc.identifier.scopus84947723711
dc.identifier.trdizintrdizin
dc.identifier.urihttps://hdl.handle.net/20.500.12645/5161
dc.identifier.wosWOS:000365303300001
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.subjectrestless legs syndrome
dc.titleSerum endocan levels in women with restless legs syndrome.
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameCor et Vasa
local.avesis.id7f0becb6-c553-4f91-94b5-640e6a89b792
local.avesis.response5031
local.publication.goal16 - Barış, Adalet ve Güçlü Kurumlar
local.publication.isinternational1
relation.isAuthorOfPublication960911c0-f159-46fb-acf1-866dc1b0b842
relation.isAuthorOfPublicationbd0fa92f-28bd-4264-b553-1e6c3957cf7b
relation.isAuthorOfPublication72084e17-e46e-438f-925e-0a24ad5f9850
relation.isAuthorOfPublicationb04cfc56-9dea-4145-a140-c66dc7ace166
relation.isAuthorOfPublicationdbdeb67c-4919-4301-ba66-74403068133b
relation.isAuthorOfPublication777d95d8-6fb6-4952-80c1-727755625e7e
relation.isAuthorOfPublication.latestForDiscovery72084e17-e46e-438f-925e-0a24ad5f9850
relation.isGoalOfPublication7e7ce1dc-9556-4fa2-b604-c2ba181d38b9
relation.isGoalOfPublication.latestForDiscovery7e7ce1dc-9556-4fa2-b604-c2ba181d38b9
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
49-10.2147-NDT.S92771.pdf
Size:
245.35 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Yayınlar - Eserler
Diş Hekimliği Fakültesi
Tıp Fakültesi
TR Dizin İndeksli Yayınlar Koleksiyonu