Publication: Merkel Cell Carcinoma
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Date
2023-01-01
Authors
Sönmez Ergün, Selma
Kirazoğlu, Ahmet
Akdemir, Osman Cemil
Su Küçük, Özlem
Altınok, Pelin
Yıldız, Pelin
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Abstract
Merkel cell carcinoma (MCC) is a rare tumor that arises from mechanoreceptor Merkel cells. Ultraviolet exposure, immunosuppression and Merkel cell polyoma virus play a significant role in tumor pathogenesis. Although it typically presents as an initially indolent growing, painless solitary lesion, the course of MCC may be aggressive due to the nodal invasion, distant metastasis and high recurrence rates. We presented a case of MCC with a background history of rheumatoid arthritis treated with immunosuppressive therapy for many years who had necrotizing granulomatous lymphadenitis.
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Keywords
Merkel cell carcinoma, immunosuppression, therapy
Citation
Sönmez Ergün S, Kirazoğlu A, Akdemir OC, Küçük ÖS, Altınok P, Yıldız P. Merkel Cell Carcinoma. Bezmialem Science 2023;11(1):128-31