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Use of Mesna in the treatment of ossicular chain fixation related to tympanosclerosis; prospective, clinical study.

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Objective: Mesna is a thiol compound effective in the connective tissue, which is used for its chemical dissector, mucolytic, mucosal damage preventive and antioxidant effects. The aim of this study was to investigate Mesna-s effects in easy dissection in type 4 tympanosclerosis cases and in the prevention of formation of new sclerotic plaques.

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Eren S., Dogan R., Vural Ö., Tugrul S., Yenigun A., Calım Ö., Ozturan O., -Use of Mesna in the treatment of ossicular chain fixation related to tympanosclerosis; prospective, clinical study.-, American journal of otolaryngology, cilt.41, ss.102506, 2020

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