Kikuchi Fujimato Disease

Abstract

Kikuchi Fujimato disease (KFD) also know as histiocytic necrotizing lymphadenitis (HNL) is a benign, self limiting disease, which commonly affects young women under 30 years of age. Most of the cases resolve in a six month period. Laboratory and clinical findings of KFD show similarities with tuberculosis lymphadenitis, mailgn lymphoma, other malign and benign diseases. The diagnosis is established on the basis of histology of lymph node excisional biopsy. The differentiation of KFD from Sistemik Lupus Eritematosus (SLE) can sometimes be problematic because both can show similar clinical and histological features. KFD and SLE can be seen together. Forty two years-old female patient diagnosed with KFD was discussed in light of current literature.