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IN VITRO GENOTOXICITY OF CALCIUM PHOSPHATE-BASED BONE SUBSTITUTE MATERIAL ON HUMAN PERIPHERAL MONONUCLEAR LEUKOCYTES

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Altay, Mehmet Akif

Erturk, Cemil

KOÇYİĞİT, ABDÜRRAHİM

Celik, Hakim

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Background and aim: Calcium phosphate-based bone substitute materials, also called calcium phosphate cements (CPCs), are widely used in orthopedic surgery. However, the reported results regarding the genotoxicity using these materials are inadequate in literature. We evaluated the DNA damaging effects of a CPC on peripheral mononuclear leukocyte cultures.

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Altay M. A. , Erturk C., KOÇYİĞİT A., Taskin A., Celik H., -IN VITRO GENOTOXICITY OF CALCIUM PHOSPHATE-BASED BONE SUBSTITUTE MATERIAL ON HUMAN PERIPHERAL MONONUCLEAR LEUKOCYTES-, ACTA MEDICA MEDITERRANEA, cilt.29, ss.723-729, 2013

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