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Immunohistochemistry with apoptotic-antiapoptotic proteins (p53, p21, bax, bcl-2), c-kit, telomerase, and metallothionein as a diagnostic aid in benign, borderline, and malignant serous and mucinous ovarian tumors

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Date
2012-09-20T00:00:00Z
Authors
ÖZER, HATİCE
Yenicesu, Goncalmir
Arici, Sema
ÇETİN, MERAL
TUNCER, ERSİN
ÇETİN, ALİ
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Research Projects
Sustainable Development Goals
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Abstract
Background: In many tumors including ovarian cancer, cell proliferation and apoptosis are important in pathogenesis and there are many alterations in most of the genes related to the cell cycle. This study was designed to evaluate immunohistochemistry with apoptotic-antiapoptotic proteins (p53, p21, bax, and bcl-2), c-kit, telomerase, and metallothionein as a diagnostic aid in typing of benign, borderline, and malignant serous and mucinous ovarian tumors.
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ovarian tumor
Citation
ÖZER H., Yenicesu G., Arici S., ÇETİN M., TUNCER E., ÇETİN A., -Immunohistochemistry with apoptotic-antiapoptotic proteins (p53, p21, bax, bcl-2), c-kit, telomerase, and metallothionein as a diagnostic aid in benign, borderline, and malignant serous and mucinous ovarian tumors-, DIAGNOSTIC PATHOLOGY, cilt.7, 2012