Person:
BAYRAM, MEHMET

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MEHMET
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  • PublicationOpen Access
    [Relationship between symptoms of obstructive sleep apnea syndrome and traffic accidents in the city drivers].
    (2013-01-01) Akkoyunlu, MUHAMMED EMİN; KART, L; ULUDAĞ, M; Bayram, MEHMET; ALISHA, G; ÖZÇELIK, H; Karaköse, FATMANUR; SEZER, M; AKKOYUNLU, MUHAMMED EMİN; BAYRAM, MEHMET; OKYALTIRIK, FATMANUR
    Introduction: There is a high tendency for traffic accidents in patients with obstructive sleep apnea syndrome (OSAS). Thus it's recommended to investigate OSAS symptoms before certification of professional drivers. However, to what degree OSAS symptoms predict traffic accidents is not clear. We aimed to investigate the relationship between OSAS symptoms and traffic accidents. Materials and methods: Five hundred twenty bus drivers working at Istanbul Electricity, Tramway and Tunnel (IETT) general management were randomly selected. Berlin questionnaire was applied which included demographic data, accident ratios, total duration in profession, duration of working in a day and OSAS symptoms. Epworth sleepiness score (ESS) test was applied to assess day time slepiness. Results: All drivers were male. Snoring were present in 324 (65.7%) of participants. Traffic accident history were present in 259 (49.7%) of drivers. Significant relationship was present between traffic accident and only daytime sleepiness among the OSAS symptoms. The mean of accident/year ratio of all participants were 0.092. Mean of ESS was 7.3 ± 3.2 for all participants. There is a positive correlation between ESS and accident/year ratio (r= 0.57, p= 0.012). Conclusion: Only daytime sleepiness among OSAS symptoms is related with traffic accident. The questioning of OSAS symptoms alone is inadequate to estimate traffic accident risk. Thus further consideration more than symptom questioning is needed at phase of authorization of professional drivers to detect OSAS.
  • PublicationOpen Access
    Opioid-free total intravenous anesthesia with propofol, dexmedetomidine and lidocaine infusions for laparoscopic cholecystectomy: a prospective, randomized, double-blinded study
    (2015-05-01) BAKAN, Mefkur; UMUTOGLU, Tarik; TOPUZ, Ufuk; UYSAL, HARUN; Bayram, MEHMET; Kadioglu, HÜSEYİN; SALIHOGLU, Ziya; UYSAL, HARUN; BAYRAM, MEHMET; KADIOĞLU, HÜSEYİN
    Justificativa e objetivos: O uso de opioides no período intraoperatório pode estar associado à hiperalgesia e ao aumento do consumo de analgésicos no período pós-operatório. Efeitos colaterais como náusea e vômito no período pós-operatório, por causa do uso perioperatório de opioides, podem prolongar a alta. Nossa hipótese foi que a anestesia venosa total com o uso de lidocaína e dexmedetomidina em substituic¸ão a opioides pode ser uma técnica opcional para a colecistectomia laparoscópica e estaria associada a uma menor solicitac¸ão de fentanil e incidência de náusea e vômito no período pós-operatório. Métodos: Foram programados para colecistectomia laparoscópica eletiva 80 pacientes adultos, estado físico ASA I-II. Os pacientes foram randomicamente alocados em dois grupos para receber anestesia livre de opioides com infusões intravenosas (IV) de dexmedetomidina, lidocaína e propofol (Grupo DL) ou anestesia baseada em opioides com infusões de remifentanil e propofol (Grupo RF). Todos os pacientes receberam um regime padrão de analgesia multimodal. Um dispositivo de analgesia controlada pelo paciente foi ajustado para liberar fentanil IV por seis horas após a cirurgia. O desfecho primário foi o consumo de fentanil no pós-operatório. Resultados: O consumo de fentanil na segunda hora de pós-operatório foi significativamente menor no grupo DL do que no Grupo RF, 75 ± 59g e 120 ± 94g, respectivamente, mas foi comparável na sexta hora de pós-operatório. Durante a anestesia, houve mais eventos hipotensivos no Grupo RF e mais eventos hipertensivos no grupo DL, ambos estatisticamente significativos. Apesar de apresentar um tempo de recuperac¸ão mais prolongado, o Grupo DL apresentou escores de dor e consumo de analgésicos de resgate e de ondansetrona significativamente mais baixos
  • PublicationOpen Access
    [The frequency and properties of REM related obstructive sleep apnea among the patients with mild related obstructive sleep apnea].
    (2013-01-01) Kutbay, Özçelik; Akkoyunlu, MUHAMMED EMİN; BOSTANLı, P; Bayram, MEHMET; ATAHAN, E; SEZER, M; Karaköse, FATMANUR; KART, L; AKKOYUNLU, MUHAMMED EMİN; BAYRAM, MEHMET; OKYALTIRIK, FATMANUR
    Hafif obstrüktif uyku apneli hastalarda REM ile ilişkili obstrüktif uyku apne sıklığı ve özellikleri Giriş: REM ile ilişkili obstrüktif uyku apne (OUA), “Hafif ve orta OUA olgularında daha fazla görülmesi nedeniyle uykuda solunum bozuklukları spektrumunun erken bir işareti midir?” yoksa “Tamamen ayrı bir antite midir?” sorusuyla araştırmacıların son zamanlarda oldukça dikkatini çekmektedir. Bu çalışmada, hafif OUA tanılı hastalar arasında REM ile ilişkili OUA hastalarının sıklığını ve diğer hafif OUA tanılı hastalardan farkını görmek; ayrıca REM ile ilişkili OUA hastalarında gündüz aşırı uykululuk ile apne ilişkisini değerlendirmek amaçlanmıştır. Materyal ve Metod: 1 Ağustos 2010 ile 29 Şubat 2012 tarihleri arasında Bezmialem Vakıf Üniversitesi Uyku Laboratuvarında polisomnografi tetkiki yapılan toplam 1267 hasta arasından, 134 hafif OUA [Apne hipopne indeksi (AHİ)= 5-15] tanılı hasta retrospektif olarak değerlendirildi. REM AHİ/non-REM AHİ ≥ 2 olan ve non-REM AHİ < 15 olanlar; REM ile ilişkili OUA olarak kabul edildi. Bulgular: Toplam 134 hafif OUA tanılı hastadan 80 (%59)’i REM ile ilişkili OUA olarak değerlendirildi. REM ilişkili OUA ve diğer hafif OUA’lılar yaş, cinsiyet, gündüz aşırı uykululuk, beden kitle indeksi, boyun çevresi ve ek hastalık varlığı açısından karşılaştırıldığında; REM ile ilişkili OUA grubunda yalnızca yaş ortalaması anlamlı olarak düşük bulundu. REM ile ilişkili OUA grubunun %87.3’ünde REM AHİ 15’in üzerinde; %39.3’ünde 30’un üzerindeydi. REM ile ilişkili OUA olgularında; REM AHİ ile gündüz aşırı uykululuk semptomu arasında anlamlı ilişki saptanmadı (p= 0.81). Sonuç: Hafif OUA olguları arasında, REM ile ilişkili OUA grubunun yaş ortalamasının daha düşük olması, REM OUA’nın “uykuda solunum bozuklukları spektrumunun erken bir işareti” olabileceğini düşündürebilir. Bu grup hastaların klinik takibinin bu sorunun cevabı açısından yararlı olacağı kanısındayız.
  • PublicationOpen Access
    Management of thoracic trauma in emergency service: Analysis of 1139 cases
    (2013-01-01) DÖNGEL, İsa; COŞKUN, ABUZER; OZBAY, Sedat; Bayram, MEHMET; ATLI, Bahri; BAYRAM, MEHMET
    Objective: Thoracic trauma is a common cause of significant morbidity and mortality. This study presents a series of thoracic trauma with the aim to assess epidemiologic features, distribution of pathologies, additional systemic injuries, diagnosis, management and outcome. Methodology: Between January 2007 and December 2011, all patients with thorax trauma admitted to the emergency service of our hospital were retrospectively reviewed with respect to age, gender, etiological factors, distribution of pathologies, additional systemic injuries, diagnosis, treatment modalities, referral and outcome. Results: A total of 1139 patients with thorax trauma were included in the study. Of these, 698 (61.3%) were male and 441 (38.7%) were female, and the average age was 54.17±17.39 years. 1090 (95.7%) of the patients had blunt trauma, whereas 49 (4.3%) had penetrating trauma. Etiological factors were falls in 792 (69.5%), motor vehicle accidents in 259 (22.8%), animal related accidents in 39 (3.4%) and penetrating injuries in 49 (4.2%) patients. It was found that 229 (20%) patients had single, 101 (8.9%) had double, 5 (3%) had three or more, 10 (0.9%) had bilateral rib fractures and 19 (1.7%) had sternal fracture. Pneumothorax was diagnosed in 58 (5.1%) patients, whereas hemothorax, hemopneuomothorax and other system injuries were diagnosed in 36 (3.2%), 38(3.3%) and 292 (25.6%) respectively. In our series, thirteen patients (mortality rate 1.1%) died as result of hemorrhagic shock (n=8), respiratory distress (n=3) and severe multiple trauma (n=2). Conclusion: Although majority of the patients with thorax trauma receive treatment as outpatients; thoracic traumas may be a life threatening condition, and should be identified and treated immediately. Mortality varies based on etiological factors, additional systemic pathologies, capabilities of the hospital especially diagnostic and treatment facilities in emergency services. We believe that a multidisciplinary approach to the patients with severe thorax trauma, and the opportunities of emergency bedside thoracotomy in emergency services will significantly reduce the morbidity and mortality.
  • PublicationOpen Access
    Brain Diffusion Changes in Obstructive Sleep Apnoea Syndrome
    (2013-01-01) Akkoyunlu, MUHAMMED EMİN; Kart, Levent; KILICARSLAN, Rukiye; Bayram, MEHMET; Aralasmak, AYŞE; Sharifov, RASUL; Alkan, ALPAY; AKKOYUNLU, MUHAMMED EMİN; BAYRAM, MEHMET; ARALAŞMAK, AYŞE; SHARIFOV, RASUL; ALKAN, ALPAY
    Background: Obstructive sleep apnoea syndrome (OSAS) is a disorder characterized by repeated apnoeic episodes during sleep. Neurocognitive changes secondary to OSAS are likely to occur due to hypoxia in certain brain locations. Advances in magnetic resonance imaging technology, such as diffusion-weighted imaging (DWI), enable non-invasive and accurate identification of OSAS-induced changes. Objective: We aimed to use DWI to investigate changes in the brain secondary to hypoxia in OSAS. Methods: Eighty-eight patients underwent polysomnography and were classified as non-OSAS, mild-moderate OSAS and severe OSAS sufferers. DWI was used to evaluate 14 areas of the brain, and apparent diffusion coefficients (ADCs) were calculated. We investigated whether there were differences in the ADC values in specific areas of the brain between the non-OSAS and OSAS patients. Results: We measured the ADC values of the 68 newly diagnosed OSAS patients (21 mild, 15 moderate and 32 severe) and of 20 healthy controls. There were significant increases in the ADC values in the hippocampus, amygdala and putamen in OSAS patients. Compared to thenon-OSAS subjects, the ADC values of the putamen in severe OSAS patients, those of the hippocampus in moderate or severe OSAS patients and those of the amygdala in moderate OSAS patients were significantly increased. A negative correlation between the lowest oxygen saturation during sleep and the ADC values of the hippocampus and amygdala was found. Conclusions: Increased ADC levels in the hippocampus, amygdala and putamen in OSAS patients indicate hypoxia and likely cause vasogenic oedema in specific regions of the brain.
  • PublicationOpen Access
    Value of Mean Platelet Volume for Disease Activity in Patients with Pulmonary Sarcoidosis
    (2017-01-01) OZCELIK, Hatice Kutbay; Bayram, MEHMET; KILIC, Elif; Akkoyunlu, MUHAMMED EMİN; SEZER, Murat; KARAKOSE, Fatmanur; YAKAR, Fatih; BAYRAM, MEHMET; AKKOYUNLU, MUHAMMED EMİN; OKYALTIRIK, FATMANUR
    Objective: We aimed to investigate the importance of mean platelet volume (MPV) as a marker for the activation and severity of disease in patients with pulmonary sarcoidosis.
  • PublicationOpen Access
    Investigation of obstructive sleep apnoea syndrome prevalence among long-distance drivers from Zonguldak, Turkey
    (2013-02-06) Akkoyunlu, Muhammed E.; Altin, Remzi; Kart, Levent; Atalay, Figen; Ornek, Tacettin; Bayram, MEHMET; Tor, Meltem; BAYRAM, MEHMET
    Background: The aim of this study was to assess the prevalence of Obstructive sleep apnoea syndrome (OSAS) in long-distance drivers located in the Zonguldak area and to show the correlation between OSAS and traffic accidents. Methods: In this study, 241 long-distance drivers who were residents of Zonguldak province were interviewed face-to-face and a questionnaire regarding OSAS symptoms, occupational histories, and numbers of accidents was administered. Body mass measurements were also taken from participants. Patients who exhibited evidence of OSAS underwent polysomnography (PSG). Results: Snoring was detected in 56% out of all participants, daytime sleepiness was observed in 26.6% and apnoea in 11.6%. All-night PSG was applied to 42 participants who had a high probability of clinical OSAS. Among these, eight had an apnoea-hypopnoea index (AHI) < 5. The prevalence of OSAS was 14.1%. There was a significant relationship between the ratio of traffic accidents per professional years and AHI (r = 0.571; p < 0.005). Conclusions: OSAS prevalence was higher among long-distance drivers in the Zonguldak region. Disease severity was directly proportional to traffic-accident risk, and thus represents a serious social problem.
  • PublicationOpen Access
    Does hormonal control obviate positive airway pressure therapy in acromegaly with sleep-disordered breathing?
    (2013-11-01) Akkoyunlu, MUHAMMED EMİN; Ilhan, MAHMUT MUZAFFER; Bayram, MEHMET; Tasan, ERTUĞRUL; YAKAR, Fatih; OZCELIK, Hatice Kutbay; KARAKOSE, Fatmanur; Kart, Levent; AKKOYUNLU, MUHAMMED EMİN; İLHAN, MAHMUT MUZAFFER; BAYRAM, MEHMET; TAŞAN, ERTUĞRUL; OKYALTIRIK, FATMANUR
    Acromegaly is a disease in which uncontrolled release of growth hormone occurs after closure of epiphyseal plates, causing changes in the body that can lead to sleep disordered breathing (SDB). No definite guidelines regarding the treatment of SDB in acromegaly are available. In this study, we aimed to investigate the prevalence of SDB in acromegaly and whether hormonal control alters the necessity of positive airway pressure (PAP) therapy in acromegaly patients with SDB. Methods: Forty-two acromegaly patients were included in the study and divided into two groups according to disease status, i.e., active or well controlled. All patients underwent polysomnography. Fourteen patients with active acromegaly were diagnosed with SDB and were evaluated for PAP therapy with polysomnography both before and 6 months after disease control was achieved. Results: Sleep-disorder breathing was diagnosed in 22 of 42 patients, 7 of 20 patients with controlled-disease and 15 of 20 patients with active diseases. There were significant reductions in respiratory disturbance index (RDI), apnea index, desaturation index, central apnea number, and rapid eye movement-phase RDI at the control polysomnography. Initially, PAP therapy was indicated in 12 of 14 patients and PAP therapy indication held in 11 patients after acromegaly control was achieved. Conclusion: Our study revealed that over half of patients with acromegaly had SDB. Furthermore, SDB severity decreases with acromegaly treatment; however, this decrease does not
  • PublicationOpen Access
    If You Know the Enemy and Your Weapons, You Need not Fear the Management of Chronic Obstructive Pulmonary Disease
    (2017-10-01) Bayram, MEHMET; AKGÜN, Metin; BAYRAM, MEHMET
    Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease that is characterized by irreversible and progressive airflow limitations [1]. The prevalence of COPD is approximately 20%, and it is one of the most important causes of morbidity and mortality [1]. Morbidity and mortality rates due to COPD are gradually increasing, and COPD has been estimated to be third leading cause of death by the end of 2020 [2]. However, it is not yet appropriately diagnosed and treated.
  • PublicationOpen Access
    Subcutaneous emphysema and pneumomediastinum complicating a dental procedure
    (2012-07-01) Döngel, Isa; Bayram, MEHMET; UYSAL, İSMAİL ÖNDER; Sunam, Guven Sadi; BAYRAM, MEHMET
    Cervicofacial emphysema and pneumomediastinum are rarely observed complications of dental interventions. The complications are associated with the use of a high-speed air-turbine dental drill. It is a potentially life-threatening condition, but the majority of cases are self-limiting and benign. We describe a patient with remarkable subcutaneous emphysema, pneumomediastinum, and partial pneumothorax after right second mandibular molar extraction. Dentists and physicians more often attribute the rapid onset of dyspnea in patients after a dental procedure to an allergic reaction to the anesthesia used during the procedure. Dentists and physicians should be aware that soft tissue emphysema can cause acute swelling of the cervicofacial region after dental procedures, which may mimic an allergic reaction.