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Raftlin, presepsin levels and thiol-disulphide homeostasis in acute appendicitis: A pilot study.

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Date
2018-11-01
Author
KOCYIGIT, ABDÜRRAHİM
MERAL, I
GULER, ERAY METİN
OZER, OF
YIGIT, M
SELEK, S
ERSOY, YELİZ EMİNE
Gultepe, BİLGE
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Article
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Abstract
Objective: To investigate some of the new inflammatory and oxidative stress markers in acute appendicitis. Methods: This clinical pilot study was conducted at the emergency department of Bezmialem Vakif University, Istanbul, Turkey, between January and July 2015, and comprised patients with definitive diagnosis of acute appendicitis and as many healthy controls. Venous blood was collected to assess white blood cell count, C-reactive protein, raftlin, presepsin, total thiol, native thiol and disulphide levels. Alvarado scores of patients were determined at the time of admission. Surgical excisions were sent for pathological examination. The results of histopathology of appendectomy specimens were categorised as non-perforated or perforated appendicitis. Results: There were130 subjects with 65(50%) patients and 65(50%) controls. Serum raftlin, presepsin, white blood count, C-reactive protein and disulphide levels were higher, and the total and native thiol levels were significantly lower in patients compared to controls (p<0.05). There was no significant difference between the non-perforated and perforated appendicitis patients regarding all the measured parameters (p>0.05) except mean Alvarado scores which were higher in perforated than non-perforated appendicitis (p<0.05). Conclusions: Inflammatory and oxidative stress markers were significantly different in acute appendicitis patients compared to healthy controls.
Subject
OZER O., GULER E. M. , KOCYIGIT A., SELEK S., YIGIT M., MERAL I., Gultepe B., ERSOY Y. E. , -Raftlin, presepsin levels and thiol-disulphide homeostasis in acute appendicitis: A pilot study.-, JPMA. The Journal of the Pakistan Medical Association, cilt.68, ss.1660-1665, 2018
URI
https://hdl.handle.net/20.500.12645/7123
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  • PubMed İndeksli Yayın Koleksiyonu [3669]
  • Sağlık Hizmetleri Meslek Yüksekokulu [274]
  • Scopus İndeksli Yayınlar Koleksiyonu [4450]
  • WoS İndeksli Yayınlar Koleksiyonu [5147]
  • Yayınlar - Eserler [9994]

BEZMIALEM VAKIF UNIVERSITY

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Bezmialem Vakıf Üniversitesi, Adnan Menderes Bulvarı Vatan Caddesi 34093 Fatih, İstanbul / TURKEY
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BEZMIALEM VAKIF UNIVERSITY

About us |Policies | Library | Contact us | Send Feedback | Sitemap | Admin

Bezmialem Vakıf Üniversitesi, Adnan Menderes Bulvarı Vatan Caddesi 34093 Fatih, İstanbul / TURKEY
Copyright © Bezmialem Vakıf Üniversitesi

Creative Commons Lisansı
Bezmialem Institutional Repository, Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

OpenAccess@BVU

Support by  UNIREPOS