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Raftlin, presepsin levels and thiol-disulphide homeostasis in acute appendicitis: A pilot study.

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dc.contributor.authorKOCYIGIT, ABDÜRRAHİM
dc.contributor.authorMERAL, I
dc.contributor.authorGULER, ERAY METİN
dc.contributor.authorOZER, OF
dc.contributor.authorYIGIT, M
dc.contributor.authorSELEK, S
dc.contributor.authorERSOY, YELİZ EMİNE
dc.contributor.authorGultepe, BİLGE
dc.date.accessioned2019-10-05T21:20:34Z
dc.date.available2019-10-05T21:20:34Z
dc.date.issued2018-11-01
dc.description.abstractObjective: To investigate some of the new inflammatory and oxidative stress markers in acute appendicitis. Methods: This clinical pilot study was conducted at the emergency department of Bezmialem Vakif University, Istanbul, Turkey, between January and July 2015, and comprised patients with definitive diagnosis of acute appendicitis and as many healthy controls. Venous blood was collected to assess white blood cell count, C-reactive protein, raftlin, presepsin, total thiol, native thiol and disulphide levels. Alvarado scores of patients were determined at the time of admission. Surgical excisions were sent for pathological examination. The results of histopathology of appendectomy specimens were categorised as non-perforated or perforated appendicitis. Results: There were130 subjects with 65(50%) patients and 65(50%) controls. Serum raftlin, presepsin, white blood count, C-reactive protein and disulphide levels were higher, and the total and native thiol levels were significantly lower in patients compared to controls (p<0.05). There was no significant difference between the non-perforated and perforated appendicitis patients regarding all the measured parameters (p>0.05) except mean Alvarado scores which were higher in perforated than non-perforated appendicitis (p<0.05). Conclusions: Inflammatory and oxidative stress markers were significantly different in acute appendicitis patients compared to healthy controls.en
dc.description.sponsorshipBezmiâlem Vakıf Üniversitesi
dc.identifier
dc.identifier.citationOZER O., GULER E. M. , KOCYIGIT A., SELEK S., YIGIT M., MERAL I., Gultepe B., ERSOY Y. E. , -Raftlin, presepsin levels and thiol-disulphide homeostasis in acute appendicitis: A pilot study.-, JPMA. The Journal of the Pakistan Medical Association, cilt.68, ss.1660-1665, 2018
dc.identifier.pubmed30410146
dc.identifier.scopus85055527767
dc.identifier.urihttps://hdl.handle.net/20.500.12645/7123
dc.identifier.wosWOS:000452026500020
dc.language.isoen
dc.rightsinfo:eu-repo/semantics/openAccessen
dc.titleRaftlin, presepsin levels and thiol-disulphide homeostasis in acute appendicitis: A pilot study.
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameCerrahpaşa Tıp Dergisi
local.avesis.idb1a01aad-d287-4618-a301-d99d8de0f58c
local.avesis.response6999
local.publication.isinternational1
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