Publication: Onychomadesis: A New Side Effect of Sodium Valproate Therapy in Children?
No Thumbnail Available
Date
2011-01-01T00:00:00Z
Authors
Authors
Icagasioglu, Dilara
AYVAZ, ADNAN
AKYOL, MELİH
Journal Title
Journal ISSN
Volume Title
Publisher
Metrics
Abstract
Valproic acid has been widely used for the treatment of epilepsy. Although usually well-tolerated, it has been associated with some side effects. Nail abnormalities are rare side effects of valproic acid. Onychomadesis refers to a complete nail separation from the nail bed, beginning at the proximal portion. We report the case of a 5-year-old female who developed onychomadesis of the fingernails after initiation of valproic acid monotherapy at a therapeutic dose for prophylaxis of convulsions-an association that has not been previously reported. We suggest that the toxic side effects of valproic acid may rarely include onychomadesis in childhood and interrupting the drug intake is essential in the treatment of onychomadesis. (Archives of Neuropsychiatry 2011; 48: 79-81)
Description
Keywords
Citation
Icagasioglu D., AYVAZ A., AKYOL M., -Onychomadesis: A New Side Effect of Sodium Valproate Therapy in Children?-, NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, cilt.48, ss.79-81, 2011