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Relation of the metabolic syndrome with proarrhythmogenic electrocardiographic parameters in patients without overt diabetes

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Date
2012-04-01
Author
Ayhan, Erkan
Kurt, Mustafa
Kaya, Ahmet
Ekinci, Mehmet
Uluganyan, MAHMUT
Uyarel, Huseyin
Altay, Servet
Guvenc, Tolga S.
Ergelen, Mehmet
Isik, Turgay
Tanboga, Ibrahim H.
Advisor
Type
Article
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Abstract
Objectives We aimed to observe the relationship of the metabolic syndrome and proarrythmogenic ECG parameters and to evaluate a possible correlation of these parameters to the metabolic syndrome score in patients without overt diabetes mellitus. Methods The study population consisted of 142 patients with the metabolic syndrome and 170 age- and gender-matched control subjects. In the ECG recordings, resting heart rate, QRS duration, corrected QT duration and corrected QT dispersion were measured. Patients were classifi ed into three groups based on number of fulfi lled metabolic syndrome criteria: group 1 (three metabolic syndrome criteria), group 2 (four metabolic syndrome criteria) and group 3 (fi ve metabolic syndrome criteria). Results Patients with the metabolic syndrome had a higher increased resting heart rate, QTcd, prolonged QRS and QTc duration. Resting heart rate increases signifi cantly parallel to the increase in the metabolic syndrome score across the groups, whilst QRS duration remained unchanged. QTc duration and QTc dispersion were signifi cantly higher in groups 2 and 3 when compared to group 1. However, no signifi cant diff erences were observed between groups 2 and 3. Conclusion We demonstrated that the metabolic syndrome and its score related with increased resting heart rate and prolonged repolarization durations in patiens without overt diabetes mellitus. These pro arrhythmogenic parameters could be used in the development of risk stratifi cation schemes for sudden cardiac death in patients with the metabolic syndrome.
Subject
Isik T., Tanboga I. H. , Kurt M., Kaya A., Ekinci M., Ayhan E., Uluganyan M., Ergelen M., Guvenc T. S. , Altay S., et al., -Relation of the metabolic syndrome with proarrhythmogenic electrocardiographic parameters in patients without overt diabetes-, ACTA CARDIOLOGICA, cilt.67, ss.195-201, 2012
URI
https://hdl.handle.net/20.500.12645/10762
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  • PubMed İndeksli Yayın Koleksiyonu [3669]
  • Scopus İndeksli Yayınlar Koleksiyonu [4450]
  • WoS İndeksli Yayınlar Koleksiyonu [5147]
  • Yayınlar - Eserler [9988]

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BEZMIALEM VAKIF UNIVERSITY

About us |Policies | Library | Contact us | Send Feedback | Sitemap | Admin

Bezmialem Vakıf Üniversitesi, Adnan Menderes Bulvarı Vatan Caddesi 34093 Fatih, İstanbul / TURKEY
Copyright © Bezmialem Vakıf Üniversitesi

Creative Commons Lisansı
Bezmialem Institutional Repository, Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

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Support by  UNIREPOS