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The diagnostic role of signal peptide-C1r/C1s, Uegf, and Bmp1-epidermal growth factor domain-containing protein 1 in non-ST-elevation acute coronary syndrome

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2015-01-01

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Sonmez, ERTAN
TURKDOGAN, Kenan Ahmet
KARABACAK, Mustafa
CİVELEK, Cemil
YILMAZ, Cahit
Ozer, Omer Faruk
ÇAVUŞ, Umut Yucel

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Abstract

Objective: Chest pain and/or electrocardiogram changes in non-ST elevation or suspicious chest pain and cardiac marker elevations are defined as non-ST-elevation acute coronary syndrome (NSTE-ACS). Serial electrocardiogram and marker follow-up are needed to make a diagnosis of NSTE-ACS and to eliminate noncoronary chest pain (NCCP). Signal peptide-C1r/C1s, Uegf, and Bmp1-epidermal growth factor domain-containing protein 1 (SCUBE1) is stored within the a granules of inactive platelets and secreted at a high rate during thrombosis. We believe that SCUBE1 may be a sensitive early diagnostic indicator in distinguishing coronary-induced chest pain from noncoronary-induced chest pain.

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Sonmez E., TURKDOGAN K. A. , KARABACAK M., CİVELEK C., YILMAZ C., Ozer O. F. , ÇAVUŞ U. Y. , -The diagnostic role of signal peptide-C1r/C1s, Uegf, and Bmp1-epidermal growth factor domain-containing protein 1 in non-ST-elevation acute coronary syndrome-, AMERICAN JOURNAL OF EMERGENCY MEDICINE, cilt.33, ss.21-24, 2015
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