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Optimization of piribedil mucoadhesive tablets for efficient therapy of Parkinson-s disease: physical characterization and ex vivo drug permeation through buccal mucosa

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Celik, BURAK
Ozdemir, Samet
Demirkoz, Asli Barla
Uner, Melike

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Objective: The aim of this study was optimization of buccal piribedil (PR) mucoadhesive tablets to improve its low bioavailability and provide controlled release for the treatment of Parkinson-s disease.

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Celik B., Ozdemir S., Demirkoz A. B. , Uner M., -Optimization of piribedil mucoadhesive tablets for efficient therapy of Parkinson-s disease: physical characterization and ex vivo drug permeation through buccal mucosa-, DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, cilt.43, ss.1836-1845, 2017

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