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An Overwiev of the Neural Crest Cells and Tumor Metastasis

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dc.contributor.authorBayindir, NİHAN
dc.contributor.authorEsrefoglu, MUKADDES
dc.contributor.institutionauthorBAYINDIR, NİHAN
dc.contributor.institutionauthorEŞREFOĞLU, MUKADDES
dc.date.accessioned2019-10-05T14:40:51Z
dc.date.available2019-10-05T14:40:51Z
dc.date.issued2016-08-01
dc.description.abstractNeural crest cells (NCCs) derived from neuroectoderm are multipotential cells. NCCs leave the neuroepithelium and migrate to various tissues by epithelial-mesenchymal transition. In this areas NCCs differentiate to variety of cells including melanocytes, glia cells, chromaffin cells. Cancer is a complex process which involves a dinamic interaction between tumor cells and surrounding micrenvironment. Cancer cells similar to neural crest cells leave their own environments and metastasize into a different tissue. The development of the neural crest and that of cancer progression share paralel morphological and molecular characteristics. Many signalling pathway and transcription factors are mutual for both processes. To investigate neural crest developmental mechanisms will provide a better understanding for cancer development, progression and metastasis.
dc.identifier10.1016/s0024-3205(00)00962-0
dc.identifier.citationBayindir N., Esrefoglu M., -An Overwiev of the Neural Crest Cells and Tumor Metastasis-, BEZMIALEM SCIENCE, cilt.4, ss.65-69, 2016
dc.identifier.urihttps://hdl.handle.net/20.500.12645/4458
dc.language.isoen
dc.subjectCancer
dc.subjectEpithelial-mesencymal transition
dc.subjectmetastasis
dc.subjectneural crest
dc.subjectReview
dc.titleAn Overwiev of the Neural Crest Cells and Tumor Metastasis
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameLIFE SCIENCES
local.avesis.id6cf27f4e-1117-4a88-8292-03c5e91ced79
local.avesis.response4328
local.org.facultyTıp Fakültesi
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
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