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Pharmacogenetics: Role of Single Nucleotide Polymorphisms

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dc.contributor.authorYÜCESAN, Emrah
dc.contributor.authorÖZTEN KANDAŞ, NUR
dc.contributor.institutionauthorÖZTEN KANDAŞ, NUR
dc.date.accessioned2020-10-22T15:55:52Z
dc.date.available2020-10-22T15:55:52Z
dc.date.issued2019-01-01T00:00:00Z
dc.description.abstractGenome sequencing methods have basically similar algorithms, although they show a few differences between the platforms. The human genome contains approximately three billion base pairs, and this amount is huge and therefore impossible to sequence at one step. However, this amount is not a problem for developed technology. Researchers break DNA into small random pieces and then sequence and reassemble. Library preparation, sequencing, bioinformatic approaches and reporting. High-quality library preparation is critical and the most important part of the next-generation sequencing workflow. Successful sequencing directly requires high-quality libraries. Sequencing is second step and all high-throughput sequencing approaches are generally based on conventional Sanger sequencing. After preparation of library and sequencing, later steps are completely computer-based (in silico) approaches called as bioinformatics.
dc.identifier.citationYÜCESAN E., ÖZTEN KANDAŞ N., -Pharmacogenetics: Role of Single Nucleotide Polymorphisms-, THERANOSTICS: METHODS AND PROTOCOLS, cilt.2054, ss.137-145, 2019
dc.identifier.doi10.1007/978-1-4939-9769-5_9
dc.identifier.pubmed31482453
dc.identifier.urihttp://hdl.handle.net/20.500.12645/23672
dc.identifier.wosWOS:000553661500010
dc.titlePharmacogenetics: Role of Single Nucleotide Polymorphisms
dc.typeArticle
dspace.entity.typePublication
local.avesis.id4d9950af-fa66-4002-934b-8301ca67aeb7
local.publication.isinternational1
relation.isAuthorOfPublicationcc769c43-7e6f-42b1-96ed-976d661dacec
relation.isAuthorOfPublication.latestForDiscoverycc769c43-7e6f-42b1-96ed-976d661dacec
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