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Association between urinary incontinence and frailty: a systematic review and meta-analysis

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dc.contributor.authorVeronese, Nicola
dc.contributor.authorSOYSAL, PINAR
dc.contributor.authorStubbs, Brendon
dc.contributor.authorMarengoni, Alessandra
dc.contributor.authorDemurtas, Jacopo
dc.contributor.authorMaggi, Stefania
dc.contributor.authorPetrovic, Mirko
dc.contributor.authorVerdejo-Bravo, Carlos
dc.contributor.institutionauthorSOYSAL, PINAR
dc.date.accessioned2020-10-22T18:04:34Z
dc.date.available2020-10-22T18:04:34Z
dc.date.issued2018-10-01T00:00:00Z
dc.description.abstractPurposeUrinary incontinence (UI) and frailty are common geriatric syndromes. Although literature increasingly supports a relationship between these two conditions, no systematic review and meta-analysis has been performed on this topic. Therefore, we aimed to investigate the potential association between UI and frailty, through a meta-analytic approach.MethodsA systematic search in major databases was undertaken until 15th March 2018 for studies reporting the association between UI and frailty. The prevalence of UI in people with frailty (vs. those without) was pooled through an odds ratio (OR) and 95% confidence intervals (CIs), with a random-effects model. The other outcomes were summarized descriptively.ResultsAmong 828 papers, 11 articles were eligible, including 3784 participants (mean age 78.2years; 55.1% women). The prevalence of UI was 39.1% in people with frailty and 19.4% in those without. A meta-analysis with five studies (1540 participants) demonstrated that UI was over twice as likely in frail people versus those without (OR 2.28; 95% CI 1.35-3.86; I-2=61%). One cross-sectional study, adjusting for potential confounders and one longitudinal study confirmed that UI is significantly associated with frailty. In two cross-sectional studies, using adjusted analyses, frailty was more common in people with UI.ConclusionUrinary incontinence is twice as common in older people with frailty compared to older people without frailty. Screening and the development of interventions for UI and frailty could prove useful for this common comorbidity.
dc.identifier.citationVeronese N., SOYSAL P., Stubbs B., Marengoni A., Demurtas J., Maggi S., Petrovic M., Verdejo-Bravo C., -Association between urinary incontinence and frailty: a systematic review and meta-analysis-, EUROPEAN GERIATRIC MEDICINE, cilt.9, ss.571-578, 2018
dc.identifier.doi10.1007/s41999-018-0102-y
dc.identifier.pubmed34654231
dc.identifier.scopus85054298973
dc.identifier.urihttp://hdl.handle.net/20.500.12645/23951
dc.identifier.wosWOS:000445464700003
dc.titleAssociation between urinary incontinence and frailty: a systematic review and meta-analysis
dc.typeArticle
dspace.entity.typePublication
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local.publication.goal16 - Barış, Adalet ve Güçlü Kurumlar
local.publication.isinternational1
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relation.isAuthorOfPublication.latestForDiscovery0e36986e-d71d-4579-a395-877af097ade5
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relation.isGoalOfPublication.latestForDiscovery7e7ce1dc-9556-4fa2-b604-c2ba181d38b9
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