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The Role of Beta-3-Adrenoceptors in Autonomic Nervous System

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dc.contributor.authorAksu, Ugur
dc.contributor.authorBELCE, Ahmet
dc.contributor.authorDEMİRCİ TANSEL, Cihan
dc.contributor.institutionauthorBELCE, AHMET
dc.date.accessioned2020-10-22T15:55:59Z
dc.date.available2020-10-22T15:55:59Z
dc.date.issued2013-12-01T00:00:00Z
dc.description.abstractCatecholamines play a regulatory role in the cardiovascular system, primarily via beta (1-2)-adrenoreceptors (AR). However, in the late 1980s, the cloning of a third beta-AR subtype (beta 3-AR) in the heart has altered the conventional view on the regulation of heart function via the betaadrenergic receptors. Additionally, in blood vessels, beta 3-AR was shown to produce relaxation. Currently, the physiological role of beta 3-AR is not clearly known. Hence, the purpose of this review is to summarize the physiological evidences supporting the functional roles of beta 3-AR in various tissues, particularly cardiac and vascular. In addition, this review discusses the potential role of beta 3-AR in obesity and insulin resistance and emphasizes their putative involvement as new therapeutic targets.
dc.identifier.citationAksu U., BELCE A., DEMİRCİ TANSEL C., -The Role of Beta-3-Adrenoceptors in Autonomic Nervous System-, BEZMIALEM SCIENCE, cilt.1, ss.16-20, 2013
dc.identifier.doi10.5152/bs.2013.1387
dc.identifier.urihttp://hdl.handle.net/20.500.12645/23676
dc.identifier.urihttp://www.bezmialemscience.org/archives/archive-detail/article-preview/the-role-of-beta-3-adrenoceptors-in-autonomic-nerv/20457
dc.identifier.wosWOS:000218631800003
dc.subjectBeta-3-Adrenoceptors
dc.titleThe Role of Beta-3-Adrenoceptors in Autonomic Nervous System
dc.typeArticle
dspace.entity.typePublication
local.avesis.id4e78c3ee-bba4-45b5-b3fb-50bff0843424
local.indexed.atWOS
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
local.publication.isinternational1
relation.isAuthorOfPublication1dab0171-c804-4401-9ea2-2933335498cf
relation.isAuthorOfPublication.latestForDiscovery1dab0171-c804-4401-9ea2-2933335498cf
relation.isGoalOfPublication9c198c48-b603-4e2f-8366-04edcfc1224c
relation.isGoalOfPublication.latestForDiscovery9c198c48-b603-4e2f-8366-04edcfc1224c

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